Proteins in urine, for example, could help detect early signs of coronary heart disease (CHD), tell whether the body is rejecting a transplanted kidney and show whether someone has sleeping sickness. Marcus said, "The trouble with testing urine is that it's awash in salt. It can be tricky to isolate the proteins that act as biomarkers. Those biomarkers are the clues that tell whether the patient is sick or has ingested a drug."
In a review of the article, Professor Youhe Gao of Beijing Normal University wrote, "The method may have more profound implications than the authors have claimed, simply because urine is more important than most biomarker researchers realize. Urine accumulates all kinds of changes and should be a better biomarker source than blood."
The study has been published by the Proteomics-Clinical Applications.