Migraine Increases Risk of Complications During Pregnancy, Childbirth

by Hannah Joy on June 27, 2019 at 2:55 PM

Migraine increases the risk of complications during pregnancy such as risk of miscarriage, cesarean sections and giving birth to a child with low birth weight. Migraine not only affects the mother, but also the child. Newborn babies whose mothers suffered from migraine during pregnancy also have an increased risk of complications such as respiratory distress and febrile seizures, reveals a new study.

Despite the fact that many women who suffer migraines find that the number and severity of these severe headaches decrease during pregnancy, migraines are now being linked to elevated blood pressure, abortions, cesareans, preterm births and babies with low birth weight.

Migraines More Common in Women Due to Estrogen Levels

The cause of migraines has been narrowed down to estrogen and other sex hormones, according to researchers who analyzed migraines, their triggers and their relationship with sex hormones.

‘Pregnant women with migraine are at a higher risk of developing various complications such as risk of miscarriage, cesarean sections and giving birth to a child with low birth weight.’

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This is documented by an extensive register-based study recently published in the scientific journal Headache and carried out at the Department of Clinical Epidemiology at Aarhus University and Aarhus University Hospital, Denmark.

"The study shows that pregnant women with migraine more often have complications in connection with their pregnancy and childbirth than women who don't suffer from migraine. Newborn babies whose mothers suffered from migraine during pregnancy also have an increased risk of complications such as respiratory distress and febrile seizures," says Nils Skajaa, BSc, who is the study's lead author. He is employed as a researcher at the Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital.

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The researchers behind the study used the Danish health registers to identify more than 22,000 pregnant women with migraine who were in contact with a hospital as a result of their migraine or had received at least two prescriptions for migraine medication. The group was compared with an approximately ten times larger group of pregnant women without known migraine.

One finding in the study is that the risk of cesarean sections is between 15-25 per cent higher for pregnant women with migraine compared with pregnant women without migraine. Around twenty per cent of all births in Denmark are by cesarean section.

Researchers have also used the same data to deduce that migraine medication possibly prevents some of the complications. However, the results must be interpreted with caution, as Nils Skajaa explains:

"The study was not specifically designed to examine this aspect. However, we show that the risk of complications generally was lower for pregnant women with migraine who took medication when compared with the pregnant women with migraines who were not treated. This also indicates that the migraine medication isn't the cause of the complications, but rather the migraine itself. This is important knowledge for pregnant women with migraines," says Nils Skajaa.

Migraines are relatively common and affect twice as many women as men. The actual cause remains unknown, but previous research suggests that migraines may be triggered by stress, fatigue, or hormonal changes such as pregnancy.

"Paradoxically, women of childbearing age are particularly hard hit by migraines. Although experience shows that migraines become milder during pregnancy, this study emphasises that the healthcare service should be particularly aware of pregnant women with migraine," says Nils Skajaa.

Source: Eurekalert