The first ever mandible (lower jaw) implant surgery through autologous regeneration took place today at MGM Hospital in Navi Mumbai.

“Autologous cultured cell technology has created a new dimension in tissue engineering and regenerative medicine, which will diminish the burden of risks associated with auto and allografts”, says Dr. Satyen Sanghavi, Chief Scientific Officer, Regrow®.
“Regenerating patient’s own bones would be like giving her an original jaw, thus in future she can fix permanent prosthesis (denture)”, said Dr. Vaidya.
Ameloblastoma is a benign tumor of odontogenic epithelium commonly appears in the mandible. While these tumors progress slowly, the resulting lesions can cause severe abnormalities of the face and jaw. Additionally, because abnormal cell growth easily infiltrates and destroys surrounding bony tissues, wide surgical excision is required to treat this disorder. Even then, the defect remains permanent and there is no treatment available.
Post the biopsy, Dr. Vaidya sent the sample of the cell from patient’s body to “Cell Processing Center” of Regrow®, where it was isolated, differentiated and osteoblasts were cultured for five weeks. Finally, this morning, on 7th September 2010, the cultured osteoblasts cells which have the regenerative capability were implanted on the defect site of the patient. Thus, now this implant will start to form new bone growth at the defect area.
“We were very happy that the implant was done through autologous reconstruction using Meenakshi’s own body tissue, thus, making the treatment absolutely natural and safe”, said the patient’s husband, Mr. Kudekar.
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