Regardless of the presence of multiple chronic conditions, a healthy lifestyle is linked to up to 6.3 years longer life for men and 7.6 years for women, stated new research published in the open-access journal PLOS Medicine by Yogini Chudasama of the University of Leicester, and colleagues. This is the first study to quantify whether the death risk is linked to an individual and combined risk factors depend on the presence of multiple chronic conditions.
‘A healthier lifestyle was consistently associated with longer life expectancy across various individual risk factors and irrespective of the presence of multiple long-term medical conditions.’
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Several studies have associated healthy lifestyles with longer life expectancy, but it is not clear in the case of people with multiple chronic conditions. To address this knowledge gap, Chudasama and colleagues analyzed data collected between 2006 and 2010 from 480,940 adults (median age of 58 years [range 38-73]) in the UK Biobank. The participants were followed up until 2016.
The study assessed the presence of 36 chronic conditions and four self-reported lifestyle factors, namely leisure-time physical activity, smoking, diet, and alcohol consumption.
Healthy Lifestyle and Life Expectancy
In men with multiple chronic conditions:
- An unhealthy score was associated with a nonsignificant gain of 1.5 life years at 45 years compared to a very unhealthy score.
- A healthy score was linked to a statistically significant gain of 4.5 years.
- A very healthy score was associated with a statistically significant gain of 6.3 years. In women:
- 3.5 years, 6.4 years, and 7.6 years, were all statistically significant gains.
- No current smoking was associated with the largest survival benefit.
- At 45 years, current smokers had an estimated 5 to 6 years shorter life expectancy versus current non-smokers.
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The study's limitations include the observational nature of the study, which precludes conclusions regarding causality, and the non-representative sample, which was 95% white and more affluent than the general UK population.
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