About Careers Internship MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Activation of Estrogen Receptor-Beta can Help Reduce Obesity, Metabolic Diseases

by Dr. Trupti Shirole on October 17, 2016 at 4:08 PM
Font : A-A+

 Activation of Estrogen Receptor-Beta can Help Reduce Obesity, Metabolic Diseases

Safe and effective treatment for obesity is highly needed. Activating the estrogen - the primary female sex hormone - receptor-beta protein with a chemical has the potential to increase metabolism as well as help reduce obesity, suggested researchers including one of Indian-origin.

The findings showed that the activation of a chemical called beta-LGND2 by the estrogen receptor-beta can help reduce obesity and metabolic diseases in mice by converting bad fat (white fat) into good fat (brown fat).

Advertisement


This is significant as brown fat increases metabolism and may facilitate weight loss, the researchers said.

"Although there is a general misperception that obesity is not a life-threatening condition, obesity is the underlying cause for several diseases that could result in mortality," said Ramesh Narayanan, a researcher at the University of Tennessee in the US.
Advertisement

"Safe and effective treatment for obesity is highly needed, and targeting estrogen receptor-beta might be one of the strategies to safely combat obesity," Narayanan added.

To make their discovery, Narayanan and colleagues used three groups of mice.

One group was fed with normal rodent diet, while two groups were fed with high-fat diet to make them obese. One of the two high-fat diet-fed groups was treated with beta-LGND2.

The beta-LGND2-treated mice were significantly leaner than the other mice fed on high-fat diet and they also had higher body temperature and oxygen consumption, indicating higher metabolism rate.

The research was published online in The FASEB Journal.

Source: IANS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
Alarming Cesarean Section Trends in India - Convenience or Compulsion of Corporate Healthcare
Quiz on Low-Calorie Diet for Diabetes
World Heart Day in 2022- Use Heart for Every Heart
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Oophorectomy Hormone Replacement Therapy Dealing with Menopause symptoms through lifestyle changes Syndrome X Estrogen Dominance Hormonal Imbalance Perimenopause High Testosterone Level In Women / Hyperandrogenism 

Most Popular on Medindia

How to Reduce School Bag Weight - Simple Tips Color Blindness Calculator Vent Forte (Theophylline) Find a Doctor Accident and Trauma Care Sanatogen The Essence of Yoga Daily Calorie Requirements Blood Pressure Calculator Find a Hospital
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Activation of Estrogen Receptor-Beta can Help Reduce Obesity, Metabolic Diseases Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests