Risk factors or Causes

Deep Vein Thrombosis (DVT) or pelvic vein thrombosis is the most common risk factor for PE.

Deep vein thrombosis (DVT) or pelvic vein thrombosis is the most common risk factor for PE. When the clot dislodges into the blood circulation, it reaches the lungs and blocks the lung artery or one of its main sub-arteries. This condition is known as venous thromboembolism (VTE).

Thrombosis classically develops due to the following factors

Blood flow alterations –This can happen due to an injury or a surgery, pregnancy, in- dwelling venous catheters, obesity or even long -distance travel
Factors affecting the blood vessel wall such as injury or dysfunction of the inner lining
Factors affecting clotting of blood such as hormonal factors or disease conditions for e.g. genetic or acquired thrombophilia (factor V mutation)

These three factors collectively are known as Virchow’s triad.