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Desirudin - Indications, Dosage, Side Effects and Precautions

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Information about Desirudin

Generic Name : Desirudin
Up-to-date prescription details regarding Desirudin are provided here.

Pronunciation : deh-SIHR-uh-din

Learn the correct pronunciation of the Desirudin, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y44.2 Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Desirudin

International :


Revase, Iprivask

Why is Desirudin Prescribed? (Indications)

This medication is a parenteral anticoagulant, prescribed for prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism. It blocks the activity of thrombin, which helps in blood clot formation.

When should Desirudin not be taken? (Contraindications)

Contraindicated in patients with active bleeding and hypersensitivity.

What is the dosage of Desirudin?

Adults - SC- 15 mg every 12 hour with the initial dose given up to 5 to 15 min before surgery, but after induction of regional block anesthesia if used.

How should Desirudin be taken?

It comes as a solution for injection to be administered by a healthcare provider into subcutaneous layer of the skin.

What are the warnings and precautions for Desirudin?

•Caution should be exercised in patients with stomach ulcer, sugar, liver or kidney disease, stroke, bleeding in the eyes, bacterial endocarditis, during pregnancy and breastfeeding.

• Administer only through subcutaneous method.

• Activated partial thromboplastin time should be monitored in patients with increased risk of bleeding.

• Monitor patient for signs of bleeding throughout therapy.

What are the side effects of Desirudin?

Blood- Bleeding and blood clots.
Heart- Obstruction in blood circulation, low blood pressure and stroke.
Gastrointestinal- Nausea, vomiting and blood vomiting.
Miscellaneous- Injection site mass, pus, anemia, inflammation of veins, severe allergic reactions, swelling in the leg, fever, blood in urine, dizziness and nose bleed.

What are the other precautions for Desirudin?

Patient may develop with increased risk of developing an epidural or spinal blood clot, which can result in stroke.

What are the storage conditions for Desirudin?

Store it at controlled room temperature (25o to 30oC), and in an airtight container.
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