Drugs for Motion Sickness / Travel Sickness

Cyclizine is a histamine H1 inhibitor prescribed for adults and children 6 years and above for the treatment of nausea and vomiting caused due to • Motion sickness • Surgeries • Drugs like narcotic analgesics and by general anaesthetics given in the post-operative period • Radiotherapy, especially for breast cancer • Menière's disease and other forms of vestibular disturbance (rarely) Cyclizine was discovered in 1947.

Dimenhydrinate is an antihistamine and anticholinergic agent, prescribed for nausea, vomiting, and dizziness caused by motion sickness.

Meclizine is an antihistamine, prescribed for nausea, vomiting and dizziness caused by motion sickness.