Abiraterone
The serum concentration of Ponatinib can be increased when it is combined with Abiraterone.
Acetyl Sulfisoxazole
The metabolism of Ponatinib can be decreased when combined with Acetyl sulfisoxazole.
Acetyldigitoxin
Acetyldigitoxin may decrease the cardiotoxic activities of Ponatinib.
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Afatinib
The serum concentration of Afatinib can be increased when it is combined with Ponatinib.
Amiodarone
The serum concentration of Ponatinib can be increased when it is combined with Amiodarone.
Amodiaquine
The serum concentration of Amodiaquine can be increased when it is combined with Ponatinib.
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Ancestim
The risk or severity of cytotoxicity can be increased when Ancestim is combined with Ponatinib.
Apalutamide
The serum concentration of Ponatinib can be decreased when it is combined with Apalutamide.
Aprepitant
The serum concentration of Ponatinib can be increased when it is combined with Aprepitant.
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Artemether
The metabolism of Ponatinib can be decreased when combined with Artemether.
Atazanavir
The serum concentration of Ponatinib can be increased when it is combined with Atazanavir.
Atomoxetine
The metabolism of Ponatinib can be decreased when combined with Atomoxetine.
Betaxolol
The metabolism of Ponatinib can be decreased when combined with Betaxolol.
Bevacizumab
Bevacizumab may increase the cardiotoxic activities of Ponatinib.
Bevacizumab-Awwb
Bevacizumab may increase the cardiotoxic activities of Ponatinib.
Boceprevir
The serum concentration of Ponatinib can be increased when it is combined with Boceprevir.
Bortezomib
The metabolism of Ponatinib can be decreased when combined with Bortezomib.
Bosentan
The serum concentration of Ponatinib can be decreased when it is combined with Bosentan.
Bosentan Anhydrous
The serum concentration of Ponatinib can be decreased when it is combined with Bosentan.
Bosutinib
The serum concentration of Bosutinib can be increased when it is combined with Ponatinib.
Bosutinib monohydrate
The serum concentration of Bosutinib can be increased when it is combined with Ponatinib.
Brentuximab Vedotin
The serum concentration of Brentuximab vedotin can be increased when it is combined with Ponatinib.
Bupropion
The metabolism of Ponatinib can be decreased when combined with Bupropion.
Cabazitaxel
The risk or severity of adverse effects can be increased when Cabazitaxel is combined with Ponatinib.
Carbamazepine
The serum concentration of Ponatinib can be decreased when it is combined with Carbamazepine.
Celecoxib
The metabolism of Ponatinib can be decreased when combined with Celecoxib.
Ceritinib
The serum concentration of Ponatinib can be increased when it is combined with Ceritinib.
Chloroquine
The metabolism of Ponatinib can be decreased when combined with Chloroquine.
Chlorpromazine
The metabolism of Ponatinib can be decreased when combined with Chlorpromazine.
Cholecalciferol
The metabolism of Ponatinib can be decreased when combined with Cholecalciferol.
Cholic Acid
Ponatinib may decrease the excretion rate of Cholic Acid which could result in a higher serum level.
Cimetidine
The metabolism of Ponatinib can be decreased when combined with Cimetidine.
Cinacalcet
The metabolism of Ponatinib can be decreased when combined with Cinacalcet.
Citalopram
The metabolism of Ponatinib can be decreased when combined with Citalopram.
Clarithromycin
The serum concentration of Ponatinib can be increased when it is combined with Clarithromycin.
Clemastine
The metabolism of Ponatinib can be decreased when combined with Clemastine.
Clobazam
The metabolism of Ponatinib can be decreased when combined with Clobazam.
Clofezone
The metabolism of Ponatinib can be decreased when combined with Rabeprazole.
Clomipramine
The metabolism of Ponatinib can be decreased when combined with Clomipramine.
Clotrimazole
The metabolism of Ponatinib can be decreased when combined with Clotrimazole.
Clozapine
The risk or severity of adverse effects can be increased when Ponatinib is combined with Clozapine.
Cobicistat
The serum concentration of Ponatinib can be increased when it is combined with Cobicistat.
Cocaine
The metabolism of Ponatinib can be decreased when combined with Cocaine.
Colchicine
The serum concentration of Colchicine can be increased when it is combined with Ponatinib.
Conivaptan
The serum concentration of Conivaptan can be increased when it is combined with Ponatinib.
Crisaborole
The metabolism of Ponatinib can be decreased when combined with Crisaborole.
Crizotinib
The metabolism of Ponatinib can be decreased when combined with Crizotinib.
Curcumin
The serum concentration of Ponatinib can be increased when it is combined with Curcumin.
Cyclophosphamide
Cyclophosphamide may increase the cardiotoxic activities of Ponatinib.
Cyclophosphamide Anhydrous
Cyclophosphamide may increase the cardiotoxic activities of Ponatinib.
Cyclosporine
The metabolism of Ponatinib can be decreased when combined with Cyclosporine.
Dabigatran Etexilate
The serum concentration of the active metabolites of Dabigatran etexilate can be increased when Dabigatran etexilate is used in combination with Ponatinib.
Dabrafenib
The serum concentration of Ponatinib can be decreased when it is combined with Dabrafenib.
Darifenacin
The metabolism of Ponatinib can be decreased when combined with Darifenacin.
Darunavir
The serum concentration of Ponatinib can be increased when it is combined with Darunavir.
Dasatinib
The serum concentration of Ponatinib can be increased when it is combined with Dasatinib.
Dasatinib Anhydrous
The serum concentration of Ponatinib can be increased when it is combined with Dasatinib.
Deferasirox
The serum concentration of Ponatinib can be decreased when it is combined with Deferasirox.
Delavirdine
The metabolism of Ponatinib can be decreased when combined with Delavirdine.
Desipramine
The metabolism of Ponatinib can be decreased when combined with Desipramine.
Deslanoside
Deslanoside may decrease the cardiotoxic activities of Ponatinib.
Digitoxin
Digitoxin may decrease the cardiotoxic activities of Ponatinib.
Digoxin
Digoxin may decrease the cardiotoxic activities of Ponatinib.
Dihydroergotamine
The metabolism of Ponatinib can be decreased when combined with Dihydroergotamine.
Diltiazem
The metabolism of Ponatinib can be decreased when combined with Diltiazem.
Diphenhydramine
The metabolism of Ponatinib can be decreased when combined with Diphenhydramine.
Dipyrone
The risk or severity of myelosuppression can be increased when Metamizole is combined with Ponatinib.
Docetaxel
The risk or severity of adverse effects can be increased when Docetaxel is combined with Ponatinib.
DOCETAXEL ANHYDROUS
The risk or severity of adverse effects can be increased when Docetaxel is combined with Ponatinib.
Dothiepin
The metabolism of Ponatinib can be decreased when combined with Dosulepin.
Doxorubicin
The serum concentration of Doxorubicin can be increased when it is combined with Ponatinib.
Doxorubicin Hydrochloride
The serum concentration of Doxorubicin can be increased when it is combined with Ponatinib.
Doxycycline
The metabolism of Ponatinib can be decreased when combined with Doxycycline.
Doxycycline Anhydrous
The metabolism of Ponatinib can be decreased when combined with Doxycycline.
Dronedarone
The metabolism of Ponatinib can be decreased when combined with Dronedarone.
Duloxetine
The metabolism of Ponatinib can be decreased when combined with Duloxetine.
Edoxaban
The serum concentration of Edoxaban can be increased when it is combined with Ponatinib.
Efavirenz
The metabolism of Ponatinib can be decreased when combined with Efavirenz.
Eliglustat
The metabolism of Ponatinib can be decreased when combined with Eliglustat.
Eltrombopag
The serum concentration of Ponatinib can be increased when it is combined with Eltrombopag.
Enzalutamide
The serum concentration of Ponatinib can be decreased when it is combined with Enzalutamide.
Erythromycin
The metabolism of Ponatinib can be decreased when combined with Erythromycin.
Everolimus
The serum concentration of Everolimus can be increased when it is combined with Ponatinib.
Felodipine
The metabolism of Ponatinib can be decreased when combined with Felodipine.
Fluconazole
The metabolism of Ponatinib can be decreased when combined with Fluconazole.
Fluoxetine
The metabolism of Ponatinib can be decreased when combined with Fluoxetine.
Fluvoxamine
The metabolism of Ponatinib can be decreased when combined with Fluvoxamine.
Fosamprenavir
The metabolism of Ponatinib can be decreased when combined with Fosamprenavir.
Fosaprepitant
The serum concentration of Ponatinib can be increased when it is combined with Fosaprepitant.
Fosphenytoin
The serum concentration of Ponatinib can be decreased when it is combined with Fosphenytoin.
Fusidate
The serum concentration of Ponatinib can be increased when it is combined with Fusidic Acid.
Fusidic Acid
The serum concentration of Ponatinib can be increased when it is combined with Fusidic Acid.
Haloperidol
The metabolism of Ponatinib can be decreased when combined with Haloperidol.
Hypoxis hemerocallidea root extract
The serum concentration of Ponatinib can be decreased when it is combined with St. John's Wort.
Idelalisib
The serum concentration of Ponatinib can be increased when it is combined with Idelalisib.
Imatinib
The metabolism of Ponatinib can be decreased when combined with Imatinib.
Imipramine
The metabolism of Ponatinib can be decreased when combined with Imipramine.
Indinavir
The serum concentration of Ponatinib can be increased when it is combined with Indinavir.
INDINAVIR ANHYDROUS
The serum concentration of Ponatinib can be increased when it is combined with Indinavir.
Irbesartan
The metabolism of Ponatinib can be decreased when combined with Irbesartan.
Isavuconazole
The serum concentration of Ponatinib can be increased when it is combined with Isavuconazole.
Isavuconazonium
The metabolism of Ponatinib can be decreased when combined with Isavuconazonium.
Isoniazid
The metabolism of Ponatinib can be decreased when combined with Isoniazid.
Isradipine
The metabolism of Ponatinib can be decreased when combined with Isradipine.
Itraconazole
The serum concentration of Ponatinib can be increased when it is combined with Itraconazole.
Ivacaftor
The serum concentration of Ponatinib can be increased when it is combined with Ivacaftor.
Ketoconazole
The serum concentration of Ponatinib can be increased when it is combined with Ketoconazole.
Lapatinib
The metabolism of Ponatinib can be decreased when combined with Lapatinib.
Ledipasvir
The serum concentration of Ledipasvir can be increased when it is combined with Ponatinib.
Lipegfilgrastim
Ponatinib may increase the myelosuppressive activities of Lipegfilgrastim.
Lopinavir
The serum concentration of Ponatinib can be increased when it is combined with Lopinavir.
Lorcaserin
The metabolism of Ponatinib can be decreased when combined with Lorcaserin.
Losartan
The metabolism of Ponatinib can be decreased when combined with Losartan.
Lovastatin
The metabolism of Ponatinib can be decreased when combined with Lovastatin.
Luliconazole
The serum concentration of Ponatinib can be increased when it is combined with Luliconazole.
Lumacaftor
The serum concentration of Ponatinib can be decreased when it is combined with Lumacaftor.
Lumefantrine
The metabolism of Ponatinib can be decreased when combined with Lumefantrine.
Manidipine
The metabolism of Ponatinib can be decreased when combined with Manidipine.
Methadone
The metabolism of Ponatinib can be decreased when combined with Methadone.
Methotrimeprazine
The metabolism of Ponatinib can be decreased when combined with Methotrimeprazine.
Metoprolol
The metabolism of Ponatinib can be decreased when combined with Metoprolol.
Midostaurin
The metabolism of Ponatinib can be decreased when combined with Midostaurin.
Mifepristone
The serum concentration of Ponatinib can be increased when it is combined with Mifepristone.
Mirabegron
The metabolism of Ponatinib can be decreased when combined with Mirabegron.
Mitotane
The serum concentration of Ponatinib can be decreased when it is combined with Mitotane.
Nabilone
The metabolism of Ponatinib can be decreased when combined with Nabilone.
Naloxegol
The serum concentration of Naloxegol can be increased when it is combined with Ponatinib.
Nefazodone
The serum concentration of Ponatinib can be increased when it is combined with Nefazodone.
Nelfinavir
The serum concentration of Ponatinib can be increased when it is combined with Nelfinavir.
Netupitant
The serum concentration of Ponatinib can be increased when it is combined with Netupitant.
Nevirapine
The serum concentration of Ponatinib can be decreased when it is combined with Nevirapine.
Nicardipine
The metabolism of Ponatinib can be decreased when combined with Nicardipine.
Nilotinib
The metabolism of Ponatinib can be decreased when combined with Nilotinib.
Olaparib
The metabolism of Ponatinib can be decreased when combined with Olaparib.
Osimertinib
The serum concentration of Ponatinib can be increased when it is combined with Osimertinib.
Ouabain
Ouabain may decrease the cardiotoxic activities of Ponatinib.
Ovine Digoxin Immune Fab
Digoxin Immune Fab (Ovine) may decrease the cardiotoxic activities of Ponatinib.
Paclitaxel
The risk or severity of adverse effects can be increased when Paclitaxel is combined with Ponatinib.
Palbociclib
The serum concentration of Ponatinib can be increased when it is combined with Palbociclib.
Panobinostat
The serum concentration of Ponatinib can be increased when it is combined with Panobinostat.
Paroxetine
The metabolism of Ponatinib can be decreased when combined with Paroxetine.
Pazopanib
The serum concentration of Pazopanib can be increased when it is combined with Ponatinib.
Peginterferon Alfa-2b
The serum concentration of Ponatinib can be decreased when it is combined with Peginterferon alfa-2b.
Pentobarbital
The serum concentration of Ponatinib can be decreased when it is combined with Pentobarbital.
Phenobarbital
The serum concentration of Ponatinib can be decreased when it is combined with Phenobarbital.
Phenytoin
The serum concentration of Ponatinib can be decreased when it is combined with Phenytoin.
Pioglitazone
The metabolism of Ponatinib can be decreased when combined with Pioglitazone.
Posaconazole
The serum concentration of Ponatinib can be increased when it is combined with Posaconazole.
Primidone
The serum concentration of Ponatinib can be decreased when it is combined with Primidone.
Promazine
The metabolism of Ponatinib can be decreased when combined with Promazine.
Proscillaridin
Proscillaridin may decrease the cardiotoxic activities of Ponatinib.
Quinidine
The metabolism of Ponatinib can be decreased when combined with Quinidine.
Quinine
The metabolism of Ponatinib can be decreased when combined with Quinine.
Rabeprazole
The metabolism of Ponatinib can be decreased when combined with Rabeprazole.
Ranolazine
The serum concentration of Ranolazine can be increased when it is combined with Ponatinib.
Rifabutin
The serum concentration of Ponatinib can be decreased when it is combined with Rifabutin.
Rifampin
The serum concentration of Ponatinib can be decreased when it is combined with Rifampicin.
Rifapentine
The serum concentration of Ponatinib can be decreased when it is combined with Rifapentine.
Rifaximin
The serum concentration of Rifaximin can be increased when it is combined with Ponatinib.
Ritonavir
The metabolism of Ponatinib can be decreased when combined with Ritonavir.
Rolapitant
The serum concentration of Ponatinib can be increased when it is combined with Rolapitant.
Ropinirole
The metabolism of Ponatinib can be decreased when combined with Ropinirole.
Rosiglitazone
The metabolism of Ponatinib can be decreased when combined with Rosiglitazone.
Rucaparib
The metabolism of Ponatinib can be decreased when combined with Rucaparib.
Saquinavir
The serum concentration of Ponatinib can be increased when it is combined with Saquinavir.
Saquinavir Mesylate
The serum concentration of Ponatinib can be increased when it is combined with Saquinavir.
Sarilumab
The therapeutic efficacy of Ponatinib can be decreased when used in combination with Sarilumab.
Secobarbital
The metabolism of Ponatinib can be increased when combined with Secobarbital.
Sertraline
The metabolism of Ponatinib can be decreased when combined with Sertraline.
Sildenafil
The metabolism of Ponatinib can be decreased when combined with Sildenafil.
Silodosin
The serum concentration of Silodosin can be increased when it is combined with Ponatinib.
Siltuximab
The serum concentration of Ponatinib can be decreased when it is combined with Siltuximab.
Simeprevir
The serum concentration of Ponatinib can be increased when it is combined with Simeprevir.
ST. JOHN'S WORT EXTRACT
The serum concentration of Ponatinib can be decreased when it is combined with St. John's Wort.
Sulfamethoxazole
The metabolism of Ponatinib can be decreased when combined with Sulfamethoxazole.
Sulfisoxazole
The metabolism of Ponatinib can be decreased when combined with Sulfisoxazole.
Tamoxifen
The metabolism of Ponatinib can be decreased when combined with Tamoxifen.
Telaprevir
The serum concentration of Ponatinib can be increased when it is combined with Telaprevir.
Telithromycin
The serum concentration of Ponatinib can be increased when it is combined with Telithromycin.
Terbinafine
The metabolism of Ponatinib can be decreased when combined with Terbinafine.
Teriflunomide
The serum concentration of Ponatinib can be increased when it is combined with Teriflunomide.
Thioridazine
The metabolism of Ponatinib can be decreased when combined with Thioridazine.
Ticlopidine
The metabolism of Ponatinib can be decreased when combined with Ticlopidine.
Tipranavir
The metabolism of Ponatinib can be decreased when combined with Tipranavir.
Tocilizumab
The serum concentration of Ponatinib can be decreased when it is combined with Tocilizumab.
Topotecan
The serum concentration of Topotecan can be increased when it is combined with Ponatinib.
Tranylcypromine
The metabolism of Ponatinib can be decreased when combined with Tranylcypromine.
Trastuzumab
Trastuzumab may increase the cardiotoxic activities of Ponatinib.
Trimethoprim
The metabolism of Ponatinib can be decreased when combined with Trimethoprim.
Vemurafenib
The serum concentration of Ponatinib can be increased when it is combined with Vemurafenib.
Venlafaxine
The metabolism of Ponatinib can be decreased when combined with Venlafaxine.
Verapamil
The metabolism of Ponatinib can be decreased when combined with Verapamil.
Vincristine
The excretion of Vincristine can be decreased when combined with Ponatinib.
Voriconazole
The serum concentration of Ponatinib can be increased when it is combined with Voriconazole.
Ziprasidone
The metabolism of Ponatinib can be decreased when combined with Ziprasidone.
