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Modafinil Interaction with other Drugs


Modafinil is an analeptic drug, prescribed for narcolepsy, obstructive sleep apnea and shift work disorder.

Modafinil Interaction with 268 drugs. Find out more in the list below:

Acenocoumarol


The metabolism of Acenocoumarol can be decreased when combined with Modafinil.

Almotriptan


The metabolism of Almotriptan can be decreased when combined with Modafinil.

Ambrisentan


The metabolism of Ambrisentan can be decreased when combined with Modafinil.

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Aminopyrine


The metabolism of Aminophenazone can be decreased when combined with Modafinil.

Amiodarone


The metabolism of Modafinil can be decreased when combined with Amiodarone.

Amitriptyline


The metabolism of Amitriptyline can be decreased when combined with Modafinil.

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Amoxicillin


The metabolism of Amoxicillin can be decreased when combined with Modafinil.

Amoxicillin Anhydrous


The metabolism of Amoxicillin can be decreased when combined with Modafinil.

Antipyrine


The metabolism of Antipyrine can be decreased when combined with Modafinil.

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Apalutamide


The serum concentration of Modafinil can be decreased when it is combined with Apalutamide.

Apixaban


The metabolism of Apixaban can be decreased when combined with Modafinil.

Aprepitant


The serum concentration of Modafinil can be increased when it is combined with Aprepitant.

Arformoterol


The metabolism of Arformoterol can be decreased when combined with Modafinil.

Aripiprazole


The serum concentration of Aripiprazole can be decreased when it is combined with Modafinil.

Artemether


The metabolism of Artemether can be decreased when combined with Modafinil.

Atazanavir


The metabolism of Modafinil can be decreased when combined with Atazanavir.

Atomoxetine


The metabolism of Modafinil can be decreased when combined with Atomoxetine.

Atorvastatin


The risk or severity of adverse effects can be increased when Modafinil is combined with Atorvastatin.

Axitinib


The metabolism of Axitinib can be decreased when combined with Modafinil.

Azelastine


The metabolism of Azelastine can be decreased when combined with Modafinil.

Benztropine


The metabolism of Benzatropine can be decreased when combined with Modafinil.

Boceprevir


The metabolism of Modafinil can be decreased when combined with Boceprevir.

Bortezomib


The metabolism of Modafinil can be decreased when combined with Bortezomib.

Bosentan


The serum concentration of Modafinil can be decreased when it is combined with Bosentan.

Bosutinib


The serum concentration of Bosutinib can be increased when it is combined with Modafinil.

Bosutinib monohydrate


The serum concentration of Bosutinib can be increased when it is combined with Modafinil.

Brivaracetam


The metabolism of Brivaracetam can be decreased when combined with Modafinil.

Bromazepam


The metabolism of Bromazepam can be decreased when combined with Modafinil.

Bromocriptine


The risk or severity of adverse effects can be increased when Bromocriptine is combined with Modafinil.

Brompheniramine


The metabolism of Brompheniramine can be decreased when combined with Modafinil.

Bupivacaine


The metabolism of Bupivacaine can be decreased when combined with Modafinil.

Cabergoline


The risk or severity of adverse effects can be increased when Cabergoline is combined with Modafinil.

Cannabidiol


The metabolism of Cannabidiol can be decreased when combined with Modafinil.

Carbamazepine


The metabolism of Modafinil can be increased when combined with Carbamazepine.

Carbinoxamine


The metabolism of Carbinoxamine can be decreased when combined with Modafinil.

Carisoprodol


The metabolism of Carisoprodol can be decreased when combined with Modafinil.

Ceritinib


The serum concentration of Modafinil can be increased when it is combined with Ceritinib.

Cerivastatin


The serum concentration of Cerivastatin can be increased when it is combined with Modafinil.

Chloramphenicol


The metabolism of Chloramphenicol can be decreased when combined with Modafinil.

Chlormethiazole


The metabolism of clomethiazole can be decreased when combined with Modafinil.

Chlorotrianisene


The serum concentration of Chlorotrianisene can be decreased when it is combined with Modafinil.

Chlorpropamide


The metabolism of Chlorpropamide can be decreased when combined with Modafinil.

Cilostazol


The serum concentration of Cilostazol can be increased when it is combined with Modafinil.

Cisapride


The metabolism of Cisapride can be decreased when combined with Modafinil.

Citalopram


The serum concentration of Citalopram can be increased when it is combined with Modafinil.

Clarithromycin


The metabolism of Modafinil can be decreased when combined with Clarithromycin.

Clemastine


The metabolism of Modafinil can be decreased when combined with Clemastine.

Clobazam


The metabolism of Clobazam can be decreased when combined with Modafinil.

Clofezone


The metabolism of Rabeprazole can be decreased when combined with Modafinil.

Clomipramine


The metabolism of Clomipramine can be decreased when combined with Modafinil.

Clopidogrel


The serum concentration of the active metabolites of Clopidogrel can be reduced when Clopidogrel is used in combination with Modafinil resulting in a loss in efficacy.

Clotiazepam


The metabolism of Clotiazepam can be decreased when combined with Modafinil.

Clotrimazole


The metabolism of Modafinil can be decreased when combined with Clotrimazole.

Clozapine


The metabolism of Clozapine can be decreased when combined with Modafinil.

Cobicistat


The metabolism of Modafinil can be decreased when combined with Cobicistat.

Conivaptan


The serum concentration of Conivaptan can be increased when it is combined with Modafinil.

Crizotinib


The metabolism of Modafinil can be decreased when combined with Crizotinib.

Cyclophosphamide


The metabolism of Cyclophosphamide can be decreased when combined with Modafinil.

Cyclophosphamide Anhydrous


The metabolism of Cyclophosphamide can be decreased when combined with Modafinil.

Cyclosporine


The serum concentration of Cyclosporine can be decreased when it is combined with Modafinil.

Dabrafenib


The serum concentration of Modafinil can be decreased when it is combined with Dabrafenib.

Dapsone


The metabolism of Dapsone can be decreased when combined with Modafinil.

Darunavir


The metabolism of Modafinil can be decreased when combined with Darunavir.

Dasatinib


The serum concentration of Modafinil can be increased when it is combined with Dasatinib.

Dasatinib Anhydrous


The serum concentration of Modafinil can be increased when it is combined with Dasatinib.

Deferasirox


The serum concentration of Modafinil can be decreased when it is combined with Deferasirox.

Delavirdine


The metabolism of Modafinil can be decreased when combined with Delavirdine.

Desipramine


The metabolism of Desipramine can be decreased when combined with Modafinil.

Dexlansoprazole


The metabolism of Dexlansoprazole can be decreased when combined with Modafinil.

Dextromethorphan


The metabolism of Dextromethorphan can be decreased when combined with Modafinil.

Diazepam


The metabolism of Diazepam can be decreased when combined with Modafinil.

Diclofenac


The metabolism of Diclofenac can be decreased when combined with Modafinil.

Dienestrol


The serum concentration of Dienestrol can be decreased when it is combined with Modafinil.

Diethylstilbestrol


The serum concentration of Diethylstilbestrol can be decreased when it is combined with Modafinil.

Dihydroergotamine


The risk or severity of adverse effects can be increased when Dihydroergotamine is combined with Modafinil.

Diltiazem


The metabolism of Modafinil can be decreased when combined with Diltiazem.

Diphenhydramine


The metabolism of Diphenhydramine can be decreased when combined with Modafinil.

Dopamine


The metabolism of Dopamine can be decreased when combined with Modafinil.

Doxazosin


The metabolism of Doxazosin can be decreased when combined with Modafinil.

Doxepin


The metabolism of Doxepin can be decreased when combined with Modafinil.

Doxycycline


The metabolism of Modafinil can be decreased when combined with Doxycycline.

Doxycycline Anhydrous


The metabolism of Modafinil can be decreased when combined with Doxycycline.

Dronedarone


The metabolism of Modafinil can be decreased when combined with Dronedarone.

Eletriptan


The metabolism of Eletriptan can be decreased when combined with Modafinil.

Enasidenib


The metabolism of Enasidenib can be decreased when combined with Modafinil.

Enfuvirtide


The metabolism of Enfuvirtide can be decreased when combined with Modafinil.

Enzalutamide


The serum concentration of Modafinil can be decreased when it is combined with Enzalutamide.

Ergonovine


The risk or severity of adverse effects can be increased when Ergonovine is combined with Modafinil.

Ergotamine


The risk or severity of adverse effects can be increased when Ergotamine is combined with Modafinil.

Erythromycin


The metabolism of Modafinil can be decreased when combined with Erythromycin.

Escitalopram


The metabolism of Escitalopram can be decreased when combined with Modafinil.

Esomeprazole


The metabolism of Esomeprazole can be decreased when combined with Modafinil.

Estradiol


The serum concentration of Estradiol can be decreased when it is combined with Modafinil.

Estradiol 3-Benzoate


The metabolism of Estradiol benzoate can be decreased when combined with Modafinil.

Estradiol acetate


The metabolism of Estradiol acetate can be decreased when combined with Modafinil.

Estradiol Cypionate


The metabolism of Estradiol cypionate can be decreased when combined with Modafinil.

Estradiol Valerate


The metabolism of Estradiol valerate can be decreased when combined with Modafinil.

Estramustine


The serum concentration of Estramustine can be decreased when it is combined with Modafinil.

Estrogens, Conjugated (USP)


The serum concentration of Conjugated estrogens can be decreased when it is combined with Modafinil.

Estrogens, Esterified (USP)


The serum concentration of Estrogens, esterified can be decreased when it is combined with Modafinil.

Ethinyl Estradiol


The serum concentration of Ethinyl Estradiol can be decreased when it is combined with Modafinil.

Etravirine


The metabolism of Etravirine can be decreased when combined with Modafinil.

Famotidine


The metabolism of Famotidine can be decreased when combined with Modafinil.

Fluconazole


The metabolism of Modafinil can be decreased when combined with Fluconazole.

Flunitrazepam


The metabolism of Flunitrazepam can be decreased when combined with Modafinil.

Fluoxetine


The metabolism of Fluoxetine can be decreased when combined with Modafinil.

Flutamide


The metabolism of Flutamide can be decreased when combined with Modafinil.

Fluvastatin


The serum concentration of Fluvastatin can be increased when it is combined with Modafinil.

Fluvoxamine


The metabolism of Modafinil can be decreased when combined with Fluvoxamine.

Formoterol


The metabolism of Formoterol can be decreased when combined with Modafinil.

Fosamprenavir


The metabolism of Modafinil can be decreased when combined with Fosamprenavir.

Fosaprepitant


The serum concentration of Modafinil can be increased when it is combined with Fosaprepitant.

Fosphenytoin


The metabolism of Modafinil can be increased when combined with Fosphenytoin.

Fusidate


The serum concentration of Modafinil can be increased when it is combined with Fusidic Acid.

Fusidic Acid


The serum concentration of Modafinil can be increased when it is combined with Fusidic Acid.

Gliclazide


The metabolism of Gliclazide can be decreased when combined with Modafinil.

Glucosamine


The metabolism of Glucosamine can be decreased when combined with Modafinil.

Glyburide


The metabolism of Glyburide can be decreased when combined with Modafinil.

Guanfacine


The metabolism of Guanfacine can be decreased when combined with Modafinil.

Haloperidol


The metabolism of Haloperidol can be decreased when combined with Modafinil.

Hexobarbital


The metabolism of Hexobarbital can be decreased when combined with Modafinil.

Hypoxis hemerocallidea root extract


The serum concentration of Modafinil can be decreased when it is combined with St. John's Wort.

Ibrutinib


The serum concentration of Ibrutinib can be increased when it is combined with Modafinil.

Ibuprofen


The metabolism of Ibuprofen can be decreased when combined with Modafinil.

Idelalisib


The metabolism of Modafinil can be decreased when combined with Idelalisib.

Ifosfamide


The metabolism of Ifosfamide can be decreased when combined with Modafinil.

Imatinib


The metabolism of Modafinil can be decreased when combined with Imatinib.

Imipramine


The metabolism of Imipramine can be decreased when combined with Modafinil.

Indinavir


The metabolism of Modafinil can be decreased when combined with Indinavir.

INDINAVIR ANHYDROUS


The metabolism of Modafinil can be decreased when combined with Indinavir.

Indomethacin


The metabolism of Indomethacin can be decreased when combined with Modafinil.

Isavuconazole


The serum concentration of Modafinil can be increased when it is combined with Isavuconazole.

Isavuconazonium


The metabolism of Modafinil can be decreased when combined with Isavuconazonium.

Isradipine


The metabolism of Modafinil can be decreased when combined with Isradipine.

Itraconazole


The metabolism of Modafinil can be decreased when combined with Itraconazole.

Ivacaftor


The serum concentration of Modafinil can be increased when it is combined with Ivacaftor.

Ixazomib


The metabolism of Ixazomib can be decreased when combined with Modafinil.

Ketoconazole


The metabolism of Modafinil can be decreased when combined with Ketoconazole.

Lansoprazole


The metabolism of Lansoprazole can be decreased when combined with Modafinil.

Lapatinib


The metabolism of Lapatinib can be decreased when combined with Modafinil.

Levomilnacipran


The metabolism of Levomilnacipran can be decreased when combined with Modafinil.

Lisuride


The risk or severity of adverse effects can be increased when Lisuride is combined with Modafinil.

Lopinavir


The metabolism of Modafinil can be decreased when combined with Lopinavir.

Lorcaserin


The metabolism of Lorcaserin can be decreased when combined with Modafinil.

Lovastatin


The serum concentration of Lovastatin can be increased when it is combined with Modafinil.

Luliconazole


The serum concentration of Modafinil can be increased when it is combined with Luliconazole.

Lumacaftor


The metabolism of Modafinil can be increased when combined with Lumacaftor.

Macitentan


The metabolism of Macitentan can be decreased when combined with Modafinil.

Melatonin


The metabolism of Melatonin can be decreased when combined with Modafinil.

Meperidine


The metabolism of Pethidine can be decreased when combined with Modafinil.

Mephenytoin


The metabolism of Mephenytoin can be decreased when combined with Modafinil.

Mephobarbital


The metabolism of Methylphenobarbital can be decreased when combined with Modafinil.

Meprobamate


The metabolism of Meprobamate can be decreased when combined with Modafinil.

Mestranol


The serum concentration of Mestranol can be decreased when it is combined with Modafinil.

Metergoline


The risk or severity of adverse effects can be increased when Metergoline is combined with Modafinil.

Methadone


The metabolism of Methadone can be decreased when combined with Modafinil.

Methsuximide


The metabolism of Methsuximide can be decreased when combined with Modafinil.

Methylergonovine


The risk or severity of adverse effects can be increased when Methylergometrine is combined with Modafinil.

Methysergide


The risk or severity of adverse effects can be increased when Methysergide is combined with Modafinil.

Metoprolol


The metabolism of Metoprolol can be decreased when combined with Modafinil.

Mifepristone


The serum concentration of Modafinil can be increased when it is combined with Mifepristone.

Mitotane


The serum concentration of Modafinil can be decreased when it is combined with Mitotane.

Moclobemide


The metabolism of Moclobemide can be decreased when combined with Modafinil.

Nefazodone


The metabolism of Modafinil can be decreased when combined with Nefazodone.

Nelfinavir


The metabolism of Modafinil can be decreased when combined with Nelfinavir.

Netupitant


The serum concentration of Modafinil can be increased when it is combined with Netupitant.

Nevirapine


The metabolism of Modafinil can be increased when combined with Nevirapine.

Nicergoline


The risk or severity of adverse effects can be increased when Nicergoline is combined with Modafinil.

Nicotine


The metabolism of Nicotine can be decreased when combined with Modafinil.

Nicotine Polacrilex


The metabolism of Nicotine can be decreased when combined with Modafinil.

Nilotinib


The metabolism of Modafinil can be decreased when combined with Nilotinib.

Nilutamide


The metabolism of Nilutamide can be decreased when combined with Modafinil.

Nortriptyline


The metabolism of Nortriptyline can be decreased when combined with Modafinil.

Olaparib


The metabolism of Modafinil can be decreased when combined with Olaparib.

Omeprazole


The metabolism of Omeprazole can be decreased when combined with Modafinil.

Osimertinib


The serum concentration of Modafinil can be increased when it is combined with Osimertinib.

Ospemifene


The metabolism of Ospemifene can be decreased when combined with Modafinil.

Oxiconazole


The metabolism of Oxiconazole can be decreased when combined with Modafinil.

Palbociclib


The serum concentration of Modafinil can be increased when it is combined with Palbociclib.

Pantoprazole


The metabolism of Pantoprazole can be decreased when combined with Modafinil.

Pentamidine


The metabolism of Pentamidine can be decreased when combined with Modafinil.

Pentobarbital


The metabolism of Modafinil can be increased when combined with Pentobarbital.

Pergolide


The risk or severity of adverse effects can be increased when Pergolide is combined with Modafinil.

Perphenazine


The metabolism of Perphenazine can be decreased when combined with Modafinil.

Phenacetin


The metabolism of Phenacetin can be decreased when combined with Modafinil.

Phenobarbital


The metabolism of Modafinil can be increased when combined with Phenobarbital.

Phenytoin


The metabolism of Modafinil can be increased when combined with Phenytoin.

Pipothiazine


The metabolism of Pipotiazine can be decreased when combined with Modafinil.

Pitavastatin


The serum concentration of Pitavastatin can be increased when it is combined with Modafinil.

Podofilox


The metabolism of Podofilox can be decreased when combined with Modafinil.

Posaconazole


The metabolism of Modafinil can be decreased when combined with Posaconazole.

Prasugrel


The metabolism of Prasugrel can be decreased when combined with Modafinil.

Pravastatin


The serum concentration of Pravastatin can be increased when it is combined with Modafinil.

Praziquantel


The metabolism of Praziquantel can be decreased when combined with Modafinil.

Primidone


The metabolism of Modafinil can be increased when combined with Primidone.

Progesterone


The metabolism of Progesterone can be decreased when combined with Modafinil.

Proguanil


The metabolism of Proguanil can be decreased when combined with Modafinil.

Promazine


The metabolism of Promazine can be decreased when combined with Modafinil.

Propofol


The metabolism of Propofol can be decreased when combined with Modafinil.

Propranolol


The metabolism of Propranolol can be decreased when combined with Modafinil.

Quazepam


The metabolism of Quazepam can be decreased when combined with Modafinil.

Quetiapine


The metabolism of Quetiapine can be decreased when combined with Modafinil.

Quetiapine fumarate


The metabolism of Quetiapine can be decreased when combined with Modafinil.

Quinine


The metabolism of Quinine can be decreased when combined with Modafinil.

Rabeprazole


The metabolism of Rabeprazole can be decreased when combined with Modafinil.

Ramelteon


The metabolism of Ramelteon can be decreased when combined with Modafinil.

Ranitidine


The metabolism of Ranitidine can be decreased when combined with Modafinil.

Ranolazine


The metabolism of Modafinil can be decreased when combined with Ranolazine.

Rifabutin


The metabolism of Modafinil can be increased when combined with Rifabutin.

Rifampin


The metabolism of Modafinil can be increased when combined with Rifampicin.

Rifapentine


The metabolism of Modafinil can be increased when combined with Rifapentine.

Rilpivirine


The serum concentration of Rilpivirine can be decreased when it is combined with Modafinil.

Romidepsin


The metabolism of Romidepsin can be decreased when combined with Modafinil.

Rosuvastatin


The serum concentration of Rosuvastatin can be increased when it is combined with Modafinil.

Rucaparib


The metabolism of Modafinil can be decreased when combined with Rucaparib.

Saquinavir


The metabolism of Modafinil can be decreased when combined with Saquinavir.

Saquinavir Mesylate


The metabolism of Modafinil can be decreased when combined with Saquinavir.

Sarilumab


The therapeutic efficacy of Modafinil can be decreased when used in combination with Sarilumab.

Saxagliptin


The serum concentration of Saxagliptin can be decreased when it is combined with Modafinil.

Saxagliptin Anhydrous


The serum concentration of Saxagliptin can be decreased when it is combined with Modafinil.

Selegiline


The metabolism of Selegiline can be decreased when combined with Modafinil.

Sertraline


The metabolism of Sertraline can be decreased when combined with Modafinil.

Sildenafil


The metabolism of Modafinil can be decreased when combined with Sildenafil.

Siltuximab


The serum concentration of Modafinil can be decreased when it is combined with Siltuximab.

Simeprevir


The serum concentration of Modafinil can be increased when it is combined with Simeprevir.

Simvastatin


The serum concentration of Simvastatin can be increased when it is combined with Modafinil.

Sofosbuvir


The serum concentration of Sofosbuvir can be decreased when it is combined with Modafinil.

ST. JOHN'S WORT EXTRACT


The serum concentration of Modafinil can be decreased when it is combined with St. John's Wort.

Sulfisoxazole


The metabolism of Modafinil can be decreased when combined with Sulfisoxazole.

synthetic conjugated estrogens, A


The serum concentration of Synthetic Conjugated Estrogens, A can be decreased when it is combined with Modafinil.

Tamoxifen


The metabolism of Tamoxifen can be decreased when combined with Modafinil.

Tapentadol


The metabolism of Tapentadol can be decreased when combined with Modafinil.

Telaprevir


The metabolism of Modafinil can be decreased when combined with Telaprevir.

Telithromycin


The metabolism of Modafinil can be decreased when combined with Telithromycin.

Temazepam


The metabolism of Temazepam can be decreased when combined with Modafinil.

Teniposide


The metabolism of Teniposide can be decreased when combined with Modafinil.

Terbinafine


The metabolism of Terbinafine can be decreased when combined with Modafinil.

Testosterone


The metabolism of Testosterone can be decreased when combined with Modafinil.

Testosterone Cypionate


The metabolism of Testosterone cypionate can be decreased when combined with Modafinil.

Testosterone Enanthate


The metabolism of Testosterone enanthate can be decreased when combined with Modafinil.

Testosterone Undecanoate


The metabolism of Testosterone undecanoate can be decreased when combined with Modafinil.

Tetrahydrocannabinol


The metabolism of Dronabinol can be decreased when combined with Modafinil.

Thalidomide


The metabolism of Thalidomide can be decreased when combined with Modafinil.

Thioridazine


The metabolism of Thioridazine can be decreased when combined with Modafinil.

Ticlopidine


The metabolism of Modafinil can be decreased when combined with Ticlopidine.

Timolol


The metabolism of Timolol can be decreased when combined with Modafinil.

Timolol Anhydrous


The metabolism of Timolol can be decreased when combined with Modafinil.

Tipranavir


The metabolism of Tipranavir can be decreased when combined with Modafinil.

Tocilizumab


The serum concentration of Modafinil can be decreased when it is combined with Tocilizumab.

Tofacitinib


The metabolism of Tofacitinib can be decreased when combined with Modafinil.

Tolbutamide


The metabolism of Tolbutamide can be decreased when combined with Modafinil.

Tolterodine


The metabolism of Tolterodine can be decreased when combined with Modafinil.

Tolvaptan


The serum concentration of Tolvaptan can be increased when it is combined with Modafinil.

Trabectedin


The metabolism of Trabectedin can be decreased when combined with Modafinil.

Trimethadione


The metabolism of Trimethadione can be decreased when combined with Modafinil.

Trimipramine


The metabolism of Trimipramine can be decreased when combined with Modafinil.

Troglitazone


The metabolism of Troglitazone can be decreased when combined with Modafinil.

Valproate


The metabolism of Valproic Acid can be decreased when combined with Modafinil.

Valproic Acid


The metabolism of Valproic Acid can be decreased when combined with Modafinil.

Vemurafenib


The serum concentration of Modafinil can be decreased when it is combined with Vemurafenib.

Venlafaxine


The metabolism of Modafinil can be decreased when combined with Venlafaxine.

Verapamil


The metabolism of Modafinil can be decreased when combined with Verapamil.

Voriconazole


The metabolism of Modafinil can be decreased when combined with Voriconazole.

Vortioxetine


The metabolism of Vortioxetine can be decreased when combined with Modafinil.

Warfarin


The metabolism of Warfarin can be decreased when combined with Modafinil.

Zidovudine


The metabolism of Zidovudine can be decreased when combined with Modafinil.

Ziprasidone


The metabolism of Modafinil can be decreased when combined with Ziprasidone.

Zolpidem


The metabolism of Zolpidem can be decreased when combined with Modafinil.

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