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Nicardipine : Interaction with Foods, Herbs & Alcohol


Are you taking Nicardipine? Are you aware of the dangers of combining Nicardipine with certain foods, herbs, or alcohol? Drug-food-interactions are seldom discussed but can lead to undesirable side effects and potentially diminish the efficacy of the medication.

Nicardipine Interactions with Food and Herbs

Grapefruit:
  • Do not take grapefruit and its juice when you are on nicardipine.
  • This combination may increase the blood level and also alter the effectiveness of the drug (1 Trusted Source
    Bailey, D. G., Malcolm, J., Arnold, O., & Spence, J. D. (1998). Grapefruit juice-drug interactions.

    Go to source
    ).

Multivitamins plus Minerals supplement: When you are on nicardipine, avoid taking a multivitamin plus minerals supplement medication as it may reduce the effectiveness of the drug (2 Trusted Source
Drugs.com. Nicardipine and Alcohol/Food Interactions.

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).

Pleurisy Root: Pleurisy root is not recommended with most cardiovascular medications due to the presence of cardiac glycosides in this root (3Nicardipine.

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).

St. John's Wort: St. John's Wort may alter the metabolism of nicardipine and therefore should be avoided (3Nicardipine.

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).

Nicardipine Interactions with Alcohol

Drinking alcohol when using nicardipine will cause more side effects (4 Trusted Source
Wikidoc: Nicardipine.

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).

When and How to Take Nicardipine

  • Nicardipine comes in the form of a capsule or an extended-release tablet.
  • The capsule is taken 3-4 times in a day and an extended-release tablet is taken twice a day.
  • Swallow the capsules as a whole instead of crushing, chewing, or breaking them.
  • Follow the exact directions of your physician.
  • Do not stop taking medication without talking to your doctor (5 Trusted Source
    National Library of Medicine: Nicardipine MedlinePlus Drug Information.

    Go to source
    ).

References

1. Bailey, D. G., Malcolm, J., Arnold, O., & Spence, J. D. (1998). Grapefruit juice-drug interactions. British journal of clinical pharmacology, 46(2), 101-110. doi:10.1046/j.1365-2125.1998.00764.x
2. Drugs.com. Nicardipine and Alcohol/Food Interactions. https://www.drugs.com/food-interactions/nicardipine.html#
3. Nicardipine: https://wa.kaiserpermanente.org/kbase/topic.jhtml?docId=hn-10000797
4. Wikidoc: Nicardipine. https://www.wikidoc.org/index.php/Nicardipine.
5. National Library of Medicine: Nicardipine MedlinePlus Drug Information. https://medlineplus.gov/druginfo/meds/a695032.html#

Drug Name : Nicardipine

Nicardipine is a calcium channel blocker, prescribed for high blood pressure and chest pain.
We recommend consulting your doctor to verify the information presented on this page or if you need any further clarifications.


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