Topgraf Ointment is an immunosuppressant, prescribed for preventing organ rejection during transplantation. It decreases the activity of immune system to prevent an organ from rejection.
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Drug information on Topgraf Ointment (Tacrolimus) from GlaxoSmithKline Pharmaceuticals Ltd
Drug Name : Tacrolimus
Tacrolimus(Prograf) generic Topgraf Ointment is an immunosuppressant, prescribed for preventing organ rejection during transplantation. It decreases the activity of immune system to prevent an organ from rejection.
More Info about Tacrolimus
Trade Names for Tacrolimus
Topical- As 0.03% ointment- Apply a thin layer over the affected skin twice daily.
Gastrointestinal : Loss of appetite, constipation, dehydration, gastrointestinal disorder, rectal disorder, hernia, intestinal inflammation, mouth ulcer and infection.
Central Nervous System : Anxiety, dizziness, increased muscle tone, abnormal thinking, uneasiness and headache.
Heart : Vein inflammation, heart disease, dilatation of blood vessels, fainting, fast heart rate and chest pain.
Skin : Photosensitivity reaction, skin cancer, skin discoloration, skin overgrowth, skin ulcer, white patches on the skin and sweating.
Eye and ENT : Abnormal vision, eye swelling, taste perversion, tooth decay, dry eyes, ear disorder, nosebleed and eye pain.
Respiratory : Difficulty in breathing, lung disorder and inflammation of larynx.
Metabolic : Increased cholesterol level and over active thyroid.
Musculoskeletal : Joint inflammation, tendon disorder, nail disorder, neck pain and joint disorder.
Genitourinary : Unintended pregnancy and vaginal infection/inflammation.
Miscellaneous : Chills, fungal infection and swelling in the extremities.
It comes as an ointment to apply topically as directed by your physician.
Caution should be exercised in patients with heart, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
Patient may develop with increased risk of skin cancer; avoid exposure to sunlight.
Wear protective clothing and sunscreen with a high skin protection factor (SPF) to avoid sunburn.
Wear sunglasses avoid eye damage.
It may increase blood pressure; monitor blood pressure level regularly while taking this medication.
Patient may experience with the following symptoms: thirst, excessive hunger, frequent urination, blurred vision and confusion.
Avoid vaccination while taking this medication.
Avoid excess dosage.
Store it at room temperature (25°C).
♦ Safety Labeling Changes Approved By FDA