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Drug information on Zienam (Imipenem and Cilastatin) from MSD Pharmaceuticals Pvt. Ltd.

Zienam

  Injection
MSD Pharmaceuticals Pvt. Ltd.
Generic : Imipenem and Cilastatin
 325.00
500mg/500mg/1vial
1Vial

Drug Name : Imipenem and Cilastatin

Imipenem and Cilastatin(Primaxin) generic Zienam is a broad spectrum beta-lactam antibiotic, prescribed for severe body infections. Cilastatin helps Imipenem work more effectively.
More Info about Imipenem and Cilastatin


Dhanalakshmi Chinnuswamy
Further Checked by The Medindia Medical Review Team on February, 2, 2017
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Medical Condition(s) for which Zienam may be prescribed


Side effects of Zienam

•  Skin : Rash and hives.

•  Gastrointestinal: Nausea, vomiting, diarrhea, tooth or tongue discoloration and altered taste.

•  Local: Inflammation, pain, vein inflammation and severe allergic reactions.

Dosage & When it is to be taken (Indications)

Adult: IV- Susceptible infections- As imipenem: 1-2 g/day in divided doses 6-8 hourly.
Surgical prophylaxis- As imipenem: 1 g on induction of anesth, followed by 1 g 3 hours later. Additional doses of 500 mg may be given at 8 and 16 hr after induction if needed.
IM- Susceptible infections- As imipenem: 500 or 750 mg 12 hourly.
Uncomplicated gonorrhoea- As imipenem: 500 mg as single dose.

How to use Zienam?

It comes as a solution for injection to be administered by a healthcare provider either into the vein or into the large muscle.

When is Zienam not to be taken? (Contraindications)

Hypersensitivity.

Warnings and Precautions for Zienam

• Caution should be exercised in patients with history of seizures, brain injury, kidney, liver or gastrointestinal disease (especially colitis), asthma, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

• While taking this medication monitor blood sugar level in diabetic patients.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

•

Other Precautions for Zienam

Avoid excess dosage.
Avoid prolonged or long-term use of this medication.
Monitor kidney function, liver function and complete blood cell count while taking this medication.

Storage Conditions for Zienam

Normally handled and stored by healthcare provider.



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