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Drug information on Aprotin (70 mg) (Aprotinin) from VHB Lifesciences Inc.

Aprotin (70 mg)

VHB Lifesciences Inc.
Generic : Aprotinin

Drug Name : Aprotinin

Aprotinin(Emend) generic This product is derived from bovine lung tissue, which inhibits certain enzymes that increase the risk for bleeding. Aprotin (70 mg) is a protease inhibitor, prescribed for reducing blood loss and the need for blood transfusion in patients undergoing complex surgery, such as heart and liver surgery.
More Info about Aprotinin

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Medical Condition(s) for which Aprotin (70 mg) may be prescribed

Side effects of Aprotin (70 mg)

  Body as a Whole: Fever, infection, chest pain, weakness, sepsis, death, multi-system organ failure, immune system disorder.

  Heart: Low blood pressure, fast heart rate, heart attack and heart failure.

  Gastrointestinal: Nausea, constipation, vomiting, liver failure, jaundice and diarrhea.

  Blood: Anemia.

  Metabolic: Increased liver enzyme level, high blood sugar, decreased potassium levels.

  Musculoskeletal: Any event.

  Central Nervous System: Confusion, agitation, anxiety and sleeplessness.

  Respiratory: Lung disorder, pleural effusion, difficulty in breathing, increased cough, asthma and shortness of breath.

  Skin: Rash, skin discolouration.

  Genitourinary: Abnormal kidney function, urinary retention and urinary tract infection.

  Potentially Fatal:: Fatal anaphylactic reactions.

Dosage & When it is to be taken (Indications)

The 1ml initial (test) dose should be administered intravenously at least 10 minutes before the loading dose.
Adult: IV- 5 lac KIU (Kallikrein in activator unit) initially, followed by 2 lac KIU every 4 hour.

How to use Aprotin (70 mg)?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

When is Aprotin (70 mg) not to be taken? (Contraindications)


Warnings and Precautions for Aprotin (70 mg)

Test dose is recommended to all patients to assess the risk of hypersensitivity.

• Caution should be exercised in patients with history of heart surgery, liver or kidney disease, allergy, during pregnancy and lactation.

• The loading dose should be given intravenously to patients in the supine position over a 20-30 minute period. Rapid intravenous administration can cause a transient fall in blood pressure.

• Pediatric use is not recommended. Patient may develop with increased risk of severe allergic reactions if it is administered within 12 months of previous use of this medication.

Other Precautions for Aprotin (70 mg)

It should not be used in neonates and children.

Storage Conditions for Aprotin (70 mg)

Store at 2-25°C. Avoid freezing.

Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.

Disclaimer : updates the prices regularly, however despite that there may be discrepancies in the prices displayed. This can be due to many reasons including -
  • Difference in GST/local taxes
  • Change in price by the company
  • Updation of information may not have happened at the right time
For the above reasons Medindia cannot be held liable for any action taken based on the information provided by its website. The purpose of this website is to only provide the initial guidance and it does not intend to replace professional medical opinion in any manner whatsoever.

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