Aprotin (70 mg)InjectionVHB Lifesciences Inc. Generic : Aprotinin | ![]() |
Aprotinin(Emend) generic This product is derived from bovine lung tissue, which inhibits certain enzymes that increase the risk for bleeding. Aprotin (70 mg) is a protease inhibitor, prescribed for reducing blood loss and the need for blood transfusion in patients undergoing complex surgery, such as heart and liver surgery.
More Info about Aprotinin
• Body as a Whole:
Fever, infection, chest pain, weakness, sepsis, death, multi-system organ failure, immune system disorder.
• Heart:
Low blood pressure, fast heart rate, heart attack and heart failure.
• Gastrointestinal:
Nausea, constipation, vomiting, liver failure, jaundice and diarrhea.
• Blood:
Anemia.
• Metabolic:
Increased liver enzyme level, high blood sugar, decreased potassium levels.
• Musculoskeletal:
Any event.
• Central Nervous System:
Confusion, agitation, anxiety and sleeplessness.
• Respiratory:
Lung disorder, pleural effusion, difficulty in breathing, increased cough, asthma and shortness of breath.
• Skin:
Rash, skin discolouration.
• Genitourinary:
Abnormal kidney function, urinary retention and urinary tract infection.
• Potentially Fatal:: Fatal anaphylactic reactions.
The 1ml initial (test) dose should be administered intravenously at least 10 minutes before the loading dose.
Adult: IV- 5 lac KIU (Kallikrein in activator unit) initially, followed by 2 lac KIU every 4 hour.
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Hypersensitivity.
• Test dose is recommended to all patients to assess the risk of hypersensitivity.
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Caution should be exercised in patients with history of heart surgery, liver or kidney disease, allergy, during pregnancy and lactation.
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The loading dose should be given intravenously to patients in the supine position over a 20-30 minute period. Rapid intravenous administration can cause a transient fall in blood pressure.
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Pediatric use is not recommended.
Patient may develop with increased risk of severe allergic reactions if it is administered within 12 months of previous use of this medication.
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It should not be used in neonates and children.
Store at 2-25°C. Avoid freezing.
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