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Drug information on Aprotin (70 mg) (Aprotinin) from VHB Lifesciences Inc.

Aprotin (70 mg)

  Injection
VHB Lifesciences Inc.
Generic : Aprotinin
 1,482.00
1.4mg/1ml
50ml
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Medical Condition(s) for which Aprotin (70 mg) may be prescribed


Side effects of Aprotin (70 mg)

  Body as a Whole: Fever, infection, chest pain, weakness, sepsis, death, multi-system organ failure, immune system disorder.

  Heart: Low blood pressure, fast heart rate, heart attack and heart failure.

  Gastrointestinal: Nausea, constipation, vomiting, liver failure, jaundice and diarrhea.

  Blood: Anemia.

  Metabolic: Increased liver enzyme level, high blood sugar, decreased potassium levels.

  Musculoskeletal: Any event.

  Central Nervous System: Confusion, agitation, anxiety and sleeplessness.

  Respiratory: Lung disorder, pleural effusion, difficulty in breathing, increased cough, asthma and shortness of breath.

  Skin: Rash, skin discolouration.

  Genitourinary: Abnormal kidney function, urinary retention and urinary tract infection.

  Potentially Fatal:: Fatal anaphylactic reactions.

Dosage & When it is to be taken (Indications)

The 1ml initial (test) dose should be administered intravenously at least 10 minutes before the loading dose.
Adult: IV- 5 lac KIU (Kallikrein in activator unit) initially, followed by 2 lac KIU every 4 hour.

How to use Aprotin (70 mg)?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

When is Aprotin (70 mg) not to be taken? (Contraindications)

Hypersensitivity.

Warnings and Precautions for Aprotin (70 mg)

Test dose is recommended to all patients to assess the risk of hypersensitivity.

• Caution should be exercised in patients with history of heart surgery, liver or kidney disease, allergy, during pregnancy and lactation.

• The loading dose should be given intravenously to patients in the supine position over a 20-30 minute period. Rapid intravenous administration can cause a transient fall in blood pressure.

• Pediatric use is not recommended. Patient may develop with increased risk of severe allergic reactions if it is administered within 12 months of previous use of this medication.

Other Precautions for Aprotin (70 mg)

It should not be used in neonates and children.

Storage Conditions for Aprotin (70 mg)

Store at 2-25°C. Avoid freezing.


Schedule : H  Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.



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