This medication is a benzoporphyrin derivative, prescribed for neovascular age-related macular degeneration. It closes up the leaking blood vessels in the eye.
Contraindicated in patients with porphyria, and known hypersensitivity.
Adult: IV- The recommended dose is 6 mg/m2, followed by activation using laser (at a wavelength of 689 nm) 15 minutes after starting infusion.
It comes as a solution for injection to be administered by a healthcare provider into the vein.
• Caution should be exercised in patients with history of liver impairment, bile obstruction, undergoing radiation therapy, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may cause blurred vision or vision changes, do not drive a car or operate machinery while taking this medication.
• Avoid exposure to sunlight.
• Avoid getting on the skin or in the eyes.
• Most Common :
Fainting, sweating, dizziness, rash, difficulty in breathing, flushing and changes in blood pressure and heart rate, headache, uneasiness, hives, and itching.
• Ocular Treatment Site (Eye) : Inflammation of eyelid, cataracts, dry eyes, itching, decreased vision, and retinal bleeding.
• Body as a Whole : Weakness, fever, flu syndrome, back pain and sensitivity to light.
• Heart : Abnormal heart rhythm, high blood pressure, peripheral arterial disease (PAD) and varicose veins.
• Skin : Bruising.
• Gastrointestinal : Constipation, gastrointestinal cancers and nausea.
• Blood : Anemia, increase or decrease in white blood cells.
• Liver : Elevated liver function.
• Metabolic : Elevated liver enzyme.
• Musculoskeletal : Joint pain, muscle pain or weakness.
• Central Nervous System : Sensory loss, sleep disorder and fainting.
• Respiratory : Cough, inflammation of pharynx and lung infection.
• Eye and ENT : Decreased hearing, double vision and tearing disorder.
• Genitourinary : Abnormality of the prostate gland.
Avoid excess dosage.
Store it at room temperature (20 to 25°C), and in an airtight container.
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