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General Information on Trihexyphenidyl

Generic Name : Trihexyphenidyl

Pronunciation : try-hex-ee-FEN-i-dill

Latest prescription information about Trihexyphenidyl. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y46.7 | Therapeutic Classification : Antiparkinson Agents

Trade Names/Brand Names of Trihexyphenidyl

Why is Trihexyphenidyl Prescribed? (Indications)

This medication is an anticholinergic agent, prescribed for Parkinson’s disease.  It works by blocking certain nerve impulses and relaxing certain muscles.

When should Trihexyphenidyl not to be taken? (Contraindications)

Contraindicated in patients with increased eye pressure, lung, heart disease; and hypersensitivity.

What is the dosage of Trihexyphenidyl?

Adult- PO- Initial: The recommended dose is 1 mg/day in 3-4 divided doses, increased gradually up to 6-10 mg/day according to response.

How should Trihexyphenidyl be taken?

It comes as a tablet and capsule to take by mouth, with food.

What are the warnings and precautions for Trihexyphenidyl?

• Caution should be exercised in patients with history of kidney or liver disease, myasthenia gravis, heart or blood pressure problems, urinary obstruction, enlarged prostate, stomach problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, drowsiness or blurred vision, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Do not become overheated in hot weather; otherwise heat stroke may occur.

What are the side effects of Trihexyphenidyl?

   Most Common : Dryness of the mouth, blurred vision, dizziness, nausea, vomiting and nervousness.
   Eye : Blindness may occur if it is used in patients with increased eye pressure.
   Miscellaneous : Memory loss, weight loss, restlessness and sleep alterations.

What are the other precautions for Trihexyphenidyl?

Avoid excess dosage.

What are the storage conditions for Trihexyphenidyl?

Store it at room temperature.


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bantwal, India

Hello. My father is 93 years old. He has suddenly started behaving very peculiar. He sits stuck in one place and refuses to move. Even though mobile he refuses to get . He screams and abuses anybody trying to help him. If in sleep posture he does not get up. If in sitting posture he does not get up. Does not co-operate for bathing, passing natures call and any basic day to day activity. His motion is also watery.

He has had a history 10 plus years of changing mood swings. For a few days or weeks he used to be in an aggressive mood and followed by a very silent and depressive mood for another few days or weeks. This has been happening over the 10 years.

Now, for the current condition the doctor has prescribed 2 medicines 1. Serenace .....0.25 mg 2. Pacitane.....5 mg.

After giving this for 3 days now he is not urinating since morning. No urine at all. (He has a history of prostate enlargement). Now it is hot in Chennai (SUMMER. His water intake is good. He passes motion once in the night or early morning and it is watery and semi solid.

Can some doctor help me with a second opinion on this ?

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