Information about Tolcapone

Generic Name : Tolcapone
Up-to-date prescription details regarding Tolcapone are provided here.

Pronunciation : TOLE-ka-pone

Learn the correct pronunciation of the Tolcapone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y46.7 Therapeutic Classification : Antiparkinson Agents

Trade Names/Brand Names of Tolcapone

International :

Tasmar

Why is Tolcapone Prescribed? (Indications)

This medication is a catechol-O-methyl transferase (COMT) inhibitor, prescribed for Parkinson's disease along with levodopa/carbidopa. It prolongs the anti-Parkinson's effect of levodopa.

When should Tolcapone not be taken? (Contraindications)

Contraindicated in patients with rhabdomyolysis (condition in which skeletal muscle cells break down), liver disease and hypersensitivity.

What is the dosage of Tolcapone?

Initial: The recommended dose is 100 mg, three times per day.

How should Tolcapone be taken?

It comes as a tablet to take by mouth, as directed by your physician.

What are the warnings and precautions for Tolcapone?

• Caution should be exercised in patients with history of heart or kidney disease, elderly, during pregnancy and breastfeeding.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

What are the side effects of Tolcapone?

Most Common- Movement disorder, nausea, sleep disorder, involuntary movements, excessive dreaming, loss of appetite, muscular cramps, orthostatic complaints, drowsiness, diarrhea, confusion, dizziness, headache, hallucinations, vomiting, constipation, fatigue, upper respiratory tract infection, falling, increased sweating, urinary tract infection, dry mouth, abdominal pain and urine discoloration.
Central Nervous System- Depression, sensory loss, tremor, speech disorder, unsteadiness and emotional lability.
Gastrointestinal- Tooth disorder.
Body as a Whole- Flank pain, accidental injury, abdominal pain and infection.
Heart- Palpitations.
Musculoskeletal- Muscle pain.
Genitourinary- Urinary incontinence and impotence.
Respiratory- Inflammation of bronchus and pharynx.
Eye and ENT- Ringing in the ear.