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Rivaroxaban - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Rivaroxaban

Generic Name : Rivaroxaban
Pronunciation : RIV- a- ROX –a- ban
Latest prescription information about Rivaroxaban. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics
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Trade Names/Brand Names of Rivaroxaban

India : 

International : 

Xarelto Other trade names: • Xarocad • Rebless • Rivatane • Rivaban • Unclot • Viclot
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Overview of Rivaroxaban

Rivaroxaban is a blood thinner used to prevent stroke in immobilized patients who underwent recent surgery or atrial fibrillation patients. It has recently gained attention due to increased usage in COVID-19 to prevent blood clot formation.

Why is Rivaroxaban Prescribed? (Indications)

• Rivaroxaban is indicated for reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
• It is used for preventing deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE) in patients undergoing knee or hip replacement surgery.  • Rivaroxaban is indicated for reducing the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation
• It is used for preventing deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE) in patients undergoing knee or hip replacement surgery.

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When should Rivaroxaban not be taken? (Contraindications)

Rivaroxaban should not be used in patients with: • Active bleeding
• Allergy to Rivaroxaban or any of the ingredients

What is the dosage of Rivaroxaban?

For patients with atrial fibrillation or recent surgery: Take Rivaroxaban 1 time a day with evening meal.

How should Rivaroxaban be taken?

It comes as a tablet to take by mouth, with or without food.

Missed a Dose?

Stopping Rivaxoraban may increase your risk of having a stroke or forming blood clots in other parts of your body. In case of missing a dose, take the tablet immediately as soon as you remember.

What are the warnings and precautions for Rivaroxaban?

• Patients who use medications like amiodarone, azithromycin, diltiazem, dronedarone, erythromycin, felodipine, quinidine, ranolazine, or verapamil, bleeding problems should be vigilant. • Monitor kidney function, hemoglobin, hematocrit, and blood pressure regularly while taking this medication

What are the side effects of Rivaroxaban?

   Blood : Bone marrow depression.
   Gastrointestinal : Sudden onset of bleeding into the retroperitoneal space.
   Liver : Jaundice and liver inflammation.
   Immune system disorder : Hypersensitivity, anaphylactic reaction and anaphylactic shock.
   Central Nervous system : Stroke, blood clot in brain and paralysis.
   Skin : Stevens-Johnson syndrome.

What are the other precautions for Rivaroxaban?

Avoid excess dosage.

What are the Drug Interactions of Rivaroxaban?

Rivaroxaban can interact with the following drugs in various extents: • Carbamazepine • Phenytoin • Rifampin • St. John’s wort

What are the storage conditions for Rivaroxaban?

Store the medication as directed by your physician.

Last Updated : 2/12/2023



Rivaroxaban : Frequently Asked Questions

Q: What type of drug is Rivaroxaban?

A: It is a novel oral anticoagulant, also known as a blood thinning agent(1 Trusted Source
Rivaroxaban

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).

Q: What is the drug Rivaroxaban used for?

A: Rivaroxaban is prescribed for the treatment of deep vein thrombosis (DVT) and pulmonary embolism. It is also used to aid in the prevention of strokes or major blood clots in people with non-valvular atrial fibrillation(1 Trusted Source
Rivaroxaban

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).

Q: What are the dietary restrictions while taking Rivaroxaban?

A: Avoid grapefruit juice while taking rivaroxaban, as it can increase the risk of gastrointestinal bleeding(2 Trusted Source
Grapefruit - medication interactions: Forbidden fruit or avoidable consequences?

Go to source
).

Q: Does Rivaroxaban increase the risk of bleeding?

A: The most common complication of Rivaroxaban is bleeding. Patients with an increased risk of bleeding should avoid taking rivaroxaban(1 Trusted Source
Rivaroxaban

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).

Q: Is Rivaroxaban contraindicated in liver failure?

A: Rivaroxaban is not recommended for patients with liver disease who have coagulopathy and a clinically significant bleeding risk(3 Trusted Source
Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment

Go to source
).

  • 1. Rivaroxaban - (https://www.ncbi.nlm.nih.gov/books/NBK557502/ )
  • 2. Grapefruit - medication interactions: Forbidden fruit or avoidable consequences? - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589309/ )
  • 3. Anticoagulant therapy with the oral direct factor Xa inhibitors rivaroxaban, apixaban and edoxaban and the thrombin inhibitor dabigatran etexilate in patients with hepatic impairment - (https://pubmed.ncbi.nlm.nih.gov/23389892/ )
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