Rebamipide is an anti-gastritis and anti-gastric ulcer drug used for mucosal protection, healing of peptic and gastroduodenal ulcers, and treatment of gastritis.
Rebamipide is prescribed for the treatment of peptic ulcer, gastroduodenal ulcers, and gastric disorders.
It is indicated during bleeding, erosion, redness, and edema (all signs of gastric mucosal lesions) that occur in acute gastritis and acute exacerbation of chronic gastritis.
Rebamipide is an amino acid derivative that works by enhancing the mucosal defense system and scavenging free radicals in the body.
Rebamipide is also an effective and safe drug in the treatment of recurrent oral ulcers in Behcet’s disease.
Rebamipide is contraindicated in patients who are allergic to the drug.
The recommended adult dose for the drug is one 100 mg tablet.
Rebamipide should be taken orally in three divided doses, in the morning, evening and before bedtime.
• Since elderly patients may be physiologically more sensitive to this drug and more prone to gastrointestinal disorders than younger patients, take special care to when using the drug on them.
• Use the medication on pregnant or possibly pregnant women only if the anticipated therapeutic benefit is thought to outweigh any potential risk.
• Lactation should be avoided when using the medication.
• Skin: Rash, pruritus, drug-eruption-like eczema
• Gastrointestinal: Constipation, bloating, diarrhea, nausea, vomitting, stomach upset, heartburn, abdominal pain, belching, taste abnormality
• Others: Cold sweat, difficulty breathing
• Proceed immediately to the nearest emergency department if an allergic reaction occurs (difficulty in breathing or swallowing, chest tightness, swelling, skin rashes, and hives).
• Patient should be closely monitored for leukopenia, thrombocytopenia and hepatic dysfunction.
Rebamipide could interact with celecoxib or diclofenac.
Rebamipide should be stored below 25°C.
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