This medication is an immunizing agent, used to prevent rabies. The vaccine activates the body to produce antibodies against the rabies virus.
The rabies vaccine is used in patients at risk of rabies either before (pre-exposure prophylaxis) or after (post-exposure prophylaxis) bites, scratches or licks on broken skin by an animal likely to be suffering from rabies.
Contraindicated in patients with febrile illness (fever) and hypersensitivity.
Adult: IM- Pre-exposure vaccination: Primary course consists of 3 doses; 1 ml on days 0, 7 and 21 or 28. Booster dose: 1 ml based on antibody titers.
Post-exposure vaccination: Vaccinate as soon as possible after exposure and may be stopped if it is shown that the patient was not at risk.
Patients who did not receive proper primary immunization: 5 doses of 1 ml each on days 0, 3, 7, 14 and 28 (patients should also receive rabies 1g with the 1st dose); patients who have received primary immunization: 2 doses of 1 ml on days 0 and 3.
• It comes as a solution for injection to be administered by a healthcare provider.
• The injection should be administered in the arm in adults and the outer thigh in children, but not into the buttocks.
• Caution should be exercised in patients with history of allergy, poor immune system and bleeding disorder.
• Inform your doctor about your previous rabies vaccination, if any.
• Patient may develop with the following symptoms after booster dose: joint pain, nausea, malaise, severe allergic reactions, fever and vomiting; if it so consult with your doctor.
• The wound site should be washed with soap and running water as early as possible.
• The entire course should be completed even if the individual suffers from mild adverse effects.
• General: Nausea, tiredness, generalized aches, headaches, fever, allergic reactions that can be severe
• Skin: Pain, redness, swelling, itching and /or soreness at the site of injection, skin rash
• Heart: Hot flashes, palpitations
• Nervous system: Dizziness, inflammation of the brain, meninges (the covering of the brain), spinal cord or peripheral nerves, paralysis, Guillain-Barre syndrome, multiple sclerosis, vertigo, problems with vision, The nervous system related side effects are less common with the newer rabies vaccines.
• It may make you drowsy or dizzy, do not drive a car or operate machinery.
• Steroids, cancer chemotherapy or immunosuppressive drugs may reduce the development of immunity with the vaccination, thereby reducing its effectiveness.
• Chloroquine may reduce the effectiveness of the vaccine when the vaccine is administered intradermally.
• Store it at refrigerator (2°C to 8°C) and protected from light.
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