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Quinapril - Indications, Dosage, Side Effects and Precautions

Last Updated on August 11, 2022
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Information about Quinapril

Generic Name : Quinapril
Up-to-date prescription details regarding Quinapril are provided here.
Pronunciation : KWIN-a-pril
Learn the correct pronunciation of the Quinapril, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y52.4 | Therapeutic Classification : ACE Inhibitors
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Trade Names/Brand Names of Quinapril

India- Acupil, Q-Pril, Q Press.
International- Accupril.
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Why is Quinapril Prescribed? (Indications)

This medication is an angiotensin-converting enzyme (ACE) inhibitor, prescribed for high blood pressure and heart failure either alone or with other medications. It works by relaxing blood vessels.
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When should Quinapril not be taken? (Contraindications)

Contraindicated in patients with angioedema, and known hypersensitivity.

What is the dosage of Quinapril?

Adult- PO- Hypertension: The recommended initial dose is 10 or 20 mg once daily. It may be adjusted if needed.
Congestive Heart Failure: Initial dose: 5 mg orally twice a day. Maintenance: 10-20 mg orally twice a day.

How should Quinapril be taken?

It comes as a tablet to take by mouth, on an empty stomach at least 1 hour before or 2 hours after food.

What are the warnings and precautions for Quinapril?

• Caution should be exercised in patients with history of sugar, heart disease, blood vessel problems, poor blood circulation, bone marrow depression, kidney or liver impairment, stroke, recent heart attack, kidney transplant, autoimmune disease, dehydration, changes in blood minerals, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, lightheadedness, or fainting, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• It may cause a serious side effect called angioedema (life-threatening allegic reactions) with swelling of the hands, face, lips, eyes, throat, or tongue; difficulty in swallowing or breathing; or hoarseness. If it is so consult with your doctor.

• Avoid exposure to sunlight; otherwise it may cause sunburn easily.

• Avoid contact with people who have infections.

• Monitor blood pressure, blood electrolyte levels, heart function, blood sugar, kidney or liver function regularly while taking this medication.

What are the side effects of Quinapril?

   Most Common : Dizziness, coughing, fatigue, nausea , vomiting, chest pain, low blood pressure, difficulty in breathing, diarrhea, headache, muscle pain, rash and back pain.
   General : Uneasiness, viral infections and anaphylactoid reaction.
   Heart : Palpitations, dilatation of blood vessels, fast heart rate, heart failure, heart attack, stroke, chest pain, high blood pressure, low blood pressure and abnormal heart rhythm.
   Blood : Anemia.
   Gastrointestinal : Flatulence, dry mouth or throat, constipation, gastrointestinal bleeding, inflammation of pancreas, abnormal liver function, and indigestion.
   Central Nervous System : Drowsiness, fainting, nervousness, depression, sleeplessness, and tingling.
   Skin : Hair loss, increased sweating, itching, skin inflammation, sensitivity to light, and rash.
   Genitourinary : Urinary tract infection, impotence, and kidney failure.
   Respiratory : Eosinophila and lung infection.
   Miscellaneous : Abnormal vision, fluid retention, joint pain, liver inflammation, and decrease in platelets.

What are the other precautions for Quinapril?

Avoid excess dosage.

What are the storage conditions for Quinapril?

Store it at controlled room temperature (15��30�C).
Last Updated : August 11, 2022
Learn more about Quinapril's interaction with Food, Herbs and Alcohol



Quinapril : Frequently Asked Questions

Q: Does Quinapril cause dry cough?

A: Quinapril may cause a dry cough as a side effect in some people. This can be persistent and may not be relieved by any medicine. Consult a physician if the cough disturbs your sleep; they may suggest ways to manage it. Even if you stop taking Quinapril, the cough may take a few days to a month to resolve completely (1 Trusted Source
Cough induced by quinapril with resolution after changing to fosinopril

Go to source
).

Q: What is the best time of day to take Quinapril?

A: Quinapril is best taken at bedtime as it may interfere with some painkillers and indigestion medications. it is better to ask a pharmacist's advice before you buy any 'over the counter' medications (2 Trusted Source
Efficacy and Safety of Nighttime Dosing of Antihypertensives: Review of the Literature and Design of a Pragmatic Clinical Trial

Go to source
).

Q: Does Quinapril affect blood sugar levels?

A: Quinapril may affect blood sugar levels. it is necessary to monitor blood sugar levels regularly while taking this medication (3 Trusted Source
Comparison of effects of quinapril and metoprolol on glycaemic control, serum lipids, blood pressure, albuminuria and quality of life in non-insulin-dependent diabetes mellitus patients with hypertension. Swedish Quinapril Group

Go to source
).

Q:  Is Quinapril a safe drug?

A: Quinapril is generally a safe drug when taken for a short time. The long-term use of quinapril may be associated with a potentially increased risk of cancer (4 Trusted Source
Recent Warnings about Antihypertensive Drugs and Cancer Risk: Where Do They Come From?

Go to source
).

Q: Does Quinapril protect the kidneys?

A: Quinapril is commonly used to lower blood pressure, which also has the extra benefit of protecting the kidneys (5 Trusted Source
Quinapril hydrochloride effects on renal function in patients with renal dysfunction and hypertension: a drug-withdrawal study

Go to source
).

Medindia adheres to strict ethical publishing standards to provide accurate, relevant, and current health content. We source our material from reputable places such as peer-reviewed journals, academic institutions, research bodies, medical associations, and occasionally, non-profit organizations. We welcome and value audience feedback as a part of our commitment to health literacy and informed decision-making.
  • 1. Cough induced by quinapril with resolution after changing to fosinopril - (https://pubmed.ncbi.nlm.nih.gov/7919557/)
  • 2. Efficacy and Safety of Nighttime Dosing of Antihypertensives: Review of the Literature and Design of a Pragmatic Clinical Trial - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091949/ )
  • 3. Comparison of effects of quinapril and metoprolol on glycaemic control, serum lipids, blood pressure, albuminuria and quality of life in non-insulin-dependent diabetes mellitus patients with hypertension. Swedish Quinapril Group - ( https://pubmed.ncbi.nlm.nih.gov/10095796/)
  • 4. Recent Warnings about Antihypertensive Drugs and Cancer Risk: Where Do They Come From? - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215559/)
  • 5. Quinapril hydrochloride effects on renal function in patients with renal dysfunction and hypertension: a drug-withdrawal study - (https://pubmed.ncbi.nlm.nih.gov/7918140/ )
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