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General Information on Protriptyline Hydrochloride

Generic Name : Protriptyline Hydrochloride

Pronunciation : proe-TRIP-ti-leen

Latest prescription information about Protriptyline Hydrochloride. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.0 | Therapeutic Classification : Psychotherapeutics

Trade Names/Brand Names of Protriptyline Hydrochloride

International- Vivactil.

Why is Protriptyline Hydrochloride Prescribed? (Indications)

This medication is a tricyclic antidepressant, prescribed for depression. 

When should Protriptyline Hydrochloride not to be taken? (Contraindications)

Contraindicated in patients who are taking or have taken cisapride, monoamine oxidase inhibitor within 14 days; Contraindicated in patients who are in recover phase of heart attack and hypersensitivity.

What is the dosage of Protriptyline Hydrochloride?

Adult- PO- The recommended dose is 15 to 40 mg/day divided into 3 or 4 doses.

How should Protriptyline Hydrochloride be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Protriptyline Hydrochloride?

Caution should be exercised in patients with history of overactive thyroid, increased eye pressure, heart disease, kidney or liver impairment, diabetes, seizures, blood disease porphyria, enlarged prostate, difficulty in urinating, suicidal thoughts, bipolar disorder, alcoholism, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.

Avoid alcohol consumption.

Avoid becoming overheated in hot weather.

Avoid exposure to sunlight.

What are the side effects of Protriptyline Hydrochloride?

   Heart: Heart attack, stroke, heart block, abnormal heart rhythm, high blood pressure, low blood pressure, fast heart rate, and palpitations.
   Central Nervous System : Confusional states, hallucinations, disorientation, delusions, anxiety, restlessness, agitation, psychosis, sleeplessness, panic, abnormal dreams, seizures, incoordination, tremor, nerve disease, numbness, tingling, drowsiness, dizziness, weakness, fatigue, and headache.
   Allergic : Drug fever, skin rash, hives, itching, photosensitization, swelling (general, or of face and tongue).
   Blood : Bone marrow depression, decrease in white blood pressure, platelets, bruising, eosinophilia.
   Gastrointestinal : Nausea, vomiting, loss of appetite, stomach upset, diarrhea, peculiar taste, mouth ulcer, abdominal cramps, and black tongue.
   Genitourinary : Impotence, increased or decreased libido; breast enlargement in the male, breast enlargement and spontaneous milk secretion in the female, testicular swelling, elevation or depression of blood sugar levels.
   Miscellaneous : Jaundice, altered liver function, hair loss, flushing, weight gain or loss; urinary frequency, nighttime urination, perspiration.

What are the other precautions for Protriptyline Hydrochloride?

Avoid excess dosage.

What are the storage conditions for Protriptyline Hydrochloride?

Store at 20-25C.


Schedule : H

Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
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