Information about Pioglitazone
Generic Name : Pioglitazone
Up-to-date prescription details regarding Pioglitazone are provided here.
Pronunciation : PYE-oh-GLI-ta-zone
Learn the correct pronunciation of the Pioglitazone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y42.3 |
Therapeutic Classification : Antidiabetics
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Trade Names/Brand Names of Pioglitazone
India :
More... International :
Actos
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Why is Pioglitazone Prescribed? (Indications)
This medication is a thiazolidinedione antidiabetic, prescribed for type 2 diabetes in certain patients. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines. It lowers blood sugar by reducing insulin resistance.
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When should Pioglitazone not be taken? (Contraindications)
Contraindicated in patients with hypersensitivity, type 1 diabetes mellitus, symptomatic or history of heart failure, diabetic ketoacidosis, children less than 18 years, pregnancy and breastfeeding.
What is the dosage of Pioglitazone?
Adult: PO- The recommended dose is 15 to 30 mg once daily. Max: 45 mg/day.
How should Pioglitazone be taken?
It comes as a tablet to take by mouth. It is usually taken once daily with or without meals.
What are the warnings and precautions for Pioglitazone?
• Proper diet, regular exercise, and regular blood sugar testing are important for best results of this medication. Follow the diet and exercise program given to you by your health care provider.
• Caution should be exercised in patients with history of liver, heart, diabetic eye diseases, and polycystic ovary syndrome.
• Increased risk of low blood sugar when used with insulin or oral hypoglycemic.
• It may lead to edema, congestive heart failure, liver dysfunction, jaundice, and anemia.
• It may cause ovulation in premenopausal, anovulatory women.
• Monitor liver function before and during treatment, glucose control.
• Stop treatment if alanine transaminase, a liver enzyme increases and remains >3 times above the upper limit of normal or if jaundice develops.
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What are the side effects of Pioglitazone?
• Heart: Congestive heart failure.
• Central Nervous System: Headache.
• Eye and ENT: Inflammation of pharynx, swelling of the retina.
• Gastrointestinal: Tooth disorders.
• Liver: Elevated liver enzymes, inflammation or damage of liver.
• Blood: Anemia.
• Metabolic: Low glucose level with symptoms of shakiness, dizziness, sweating, headache, pale skin, hunger.
• Musculoskeletal: Bone fractures, muscle pain.
• Respiratory: Upper respiratory tract infection, sinusitis.
• Miscellaneous: Edema.
What are the other precautions for Pioglitazone?
Do not stop taking this medicine without speaking to your doctor first.
What are the storage conditions for Pioglitazone?
Oral: Keep it at room temperature and in an airtight container. Keep away from children.
Last Updated : August 11, 2022
Pioglitazone : Frequently Asked Questions
Q: Is it better to take Pioglitazone in the morning or at night?
A: Pioglitazone can be taken at any time of day, whether in the morning or evening, with or without food. Try to take it at the same time every day(1✔ ✔Trusted Source
Pioglitazone
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Q: What is the black box warning for Pioglitazone?
A: The FDA issued a blackbox warning that the use of pioglitazone for the treatment of type 2 diabetes may increase the risk of bladder cancer(2✔ ✔Trusted Source
Implications of Removing Rosiglitazone’s Black Box Warning and Restricted Access Program on the Uptake of Thiazolidinediones and Dipeptidyl Peptidase-4 Inhibitors Among Patients with Type 2 Diabetes
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Q: Does Pioglitazone reduce cholesterol?
A: Pioglitazone can help with diabetic dyslipidemia by increasing HDL cholesterol and decreasing triglycerides. Increased HDL levels may have a positive effect on reverse cholesterol transport(3✔ ✔Trusted Source
Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With Diabetes
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Q: Can Pioglitazone and metformin taken together?
A: In comparison to metformin alone, pioglitazone plus metformin significantly improved glycemic control and markers associated with increased insulin resistance and cardiovascular risk(4✔ ✔Trusted Source
A fixed-dose combination of pioglitazone and metformin: A promising alternative in metabolic control
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Q: Does Pioglitazone affect liver?
A: Pioglitazone has been linked to rare cases of acute liver injury. The liver damage caused by pioglitazone is usually reversed by discontinuing the medication(5✔ ✔Trusted Source
Pioglitazone
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78 years old,taking these 1,Metformin,1mg, 2.Pioglitazone 15mg, 3.Glimepride 2mg, 4.piosafe 30mg, 5.Pregasafe. she is taking all these medicines but her blood sugar still showing high 13 to 19. Is this the right dose and medicine?