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General Information on Pioglitazone

Generic Name : Pioglitazone

Pronunciation : PYE-oh-GLI-ta-zone

Latest prescription information about Pioglitazone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.3 | Therapeutic Classification : Antidiabetics

Why is Pioglitazone Prescribed? (Indications)

This medication is a thiazolidinedione antidiabetic, prescribed for type 2 diabetes in certain patients. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines. It lowers blood sugar by reducing insulin resistance.  

When should Pioglitazone not to be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, type 1 diabetes mellitus, symptomatic or history of heart failure, diabetic ketoacidosis, children less than 18 years, pregnancy and breastfeeding.

What is the dosage of Pioglitazone?

Adult: PO- The recommended dose is 15 to 30 mg once daily. Max: 45 mg/day.

How should Pioglitazone be taken?

It comes as a tablet to take by mouth. It is usually taken once daily with or without meals.

What are the warnings and precautions for Pioglitazone?

Proper diet, regular exercise, and regular blood sugar testing are important for best results of this medication. Follow the diet and exercise program given to you by your health care provider.

Caution should be exercised in patients with history of liver, heart, diabetic eye diseases, and polycystic ovary syndrome.

Increased risk of low blood sugar when used with insulin or oral hypoglycemic.

It may lead to edema, congestive heart failure, liver dysfunction, jaundice, and anemia.

It may cause ovulation in premenopausal, anovulatory women.

Monitor liver function before and during treatment, glucose control.

Stop treatment if alanine transaminase, a liver enzyme increases and remains >3 times above the upper limit of normal or if jaundice develops.

What are the side effects of Pioglitazone?

  Heart: Congestive heart failure.
  Central Nervous System: Headache.
  Eye and ENT: Inflammation of pharynx, swelling of the retina.
  Gastrointestinal: Tooth disorders.
  Liver: Elevated liver enzymes, inflammation or damage of liver.
  Blood: Anemia.
  Metabolic: Low glucose level with symptoms of shakiness, dizziness, sweating, headache, pale skin, hunger.
  Musculoskeletal: Bone fractures, muscle pain.
  Respiratory: Upper respiratory tract infection, sinusitis.
  Miscellaneous: Edema.

What are the other precautions for Pioglitazone?

Do not stop taking this medicine without speaking to your doctor first.

What are the storage conditions for Pioglitazone?

Oral: Keep it at room temperature and in an airtight container. Keep away from children.

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papi39, Norway

78 years old,taking these 1,Metformin,1mg, 2.Pioglitazone 15mg, 3.Glimepride 2mg, 4.piosafe 30mg, 5.Pregasafe. she is taking all these medicines but her blood sugar still showing high 13 to 19. Is this the right dose and medicine?

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