Phthalylsulfathiazole is a broad spectrum antimicrobial used for the treatment of dysentery, colitis, gastrointestinal infection and intestinal surgery.
Phthalylsulfathiazole is a broad spectrum antimicrobial used to treat different types of infections including intestinal infections like bacillary dysentery.
Phthalylsulfathiazole is indicated in the treatment of dysentery, colitis, gastrointestinal infection and intestinal surgery.
Phthalylsulfathiazole belongs to the group of drugs called sulfonamides. The drug does not get absorbed into the bloodstream from the gut.
Phthalylsulfathiazole is contraindicated in people who are allergic to the drug.
In addition, phthalylsulphathiazole should not be used in
• Patients with blood disorders
• Renal or hepatic failure
The recommended dose of phthalylsulfathiazole dose is
Day 1: 1 g every 4 hours with a maximum dose of 6 g per day
Days 3-4: 1 g every 6 hours with a maximum dose of 4 g per day
Days 5-7: 1 g every 8 hours with a maximum dose of 3 g per day
Children under 3 years: 0.2 g per kilogram body weight every 8 hours
Children above 3 years: 0.4 to 0.75 g per kilogram body weight every 4 hours
Phthalylsulfathiazole should be taken with a glass of water.
• Caution should be taken when using the drug in pregnant and breastfeeding women.
• Gastrointestinal: Nausea, stomach upset, acute toxicity
• Skin: Skin rash
• Other: Vitamin B insufficiency, agranulocytosis, aplastic anemia
Pthalylsulfathiazole could interact with the following drugs and should be avoided.
Phthalylsulfathiazole should be stored in a cool, dry place, away from children.
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