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Pemetrexed - Indications, Dosage, Side Effects and Precautions

Last Updated on August 11, 2022
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Information about Pemetrexed

Generic Name : Pemetrexed
Up-to-date prescription details regarding Pemetrexed are provided here.
Pronunciation : PEM-e-TREX-ed
Learn the correct pronunciation of the Pemetrexed, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
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Trade Names/Brand Names of Pemetrexed

India : 

International : 

Alimta
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Why is Pemetrexed Prescribed? (Indications)

This medication is an (antifolate) antineoplastic agent, prescribed for mesothelioma (cancer that develops from the protective lining of the internal tissues) and certain types of non-small cell lung cancer either alone or with other medications. It slows down the growth and the spread of cancerous tissue in the body.  

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When should Pemetrexed not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Pemetrexed?

IV: Recommended dose is 500 mg/m2 on first day of each 21-day cycle in combination with cisplatin 75 mg/m2.

How should Pemetrexed be taken?

It comes as a solution for injection, administered by a healthcare provider.

What are the warnings and precautions for Pemetrexed?

• Caution should be exercised in patients with history of pleural effusion, kidney or liver disease, elderly, pregnancy and breastfeeding.

This medication is not advisable for children.

Avoid non-steroidal anti-inflammatory medications (NSAID) drugs, while taking this medication.

Avoid contact with people who have cold or flu like infections.

Monitor kidney function regularly while taking this medication.

What are the side effects of Pemetrexed?

  Body as whole: Easy bleeding, body aches, white patches inside the mouth or in the lip region, unusual weakness, fever, chills, rapid weight gain and swelling of the body part regions.
  Skin : Pale skin, skin rash and redness at the injection site.
  Genitourinary: Less urination frequency.
  Respiratory : Chest pain and trouble in breathing.
  Gastrointestinal: Nausea, vomiting, loss of appetite, diarrhea and constipation
  Blood: Anemia.
  Central Nervous System : Sleepiness, numbness, depression and tiredness.

What are the other precautions for Pemetrexed?

It may lead to poor blood clot.

What are the storage conditions for Pemetrexed?

Normally handled and stored by healthcare provider.

Last Updated : August 11, 2022



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