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General Information on Pemetrexed

Generic Name : Pemetrexed

Pronunciation : PEM-e-TREX-ed

Latest prescription information about Pemetrexed. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names of Pemetrexed

India : 

International : 

Alimta

Why is Pemetrexed Prescribed? (Indications)

This medication is an (antifolate) antineoplastic agent, prescribed for mesothelioma (cancer that develops from the protective lining of the internal tissues) and certain types of non-small cell lung cancer either alone or with other medications. It slows down the growth and the spread of cancerous tissue in the body.  

When should Pemetrexed not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Pemetrexed?

IV: Recommended dose is 500 mg/m2 on first day of each 21-day cycle in combination with cisplatin 75 mg/m2.

How should Pemetrexed be taken?

It comes as a solution for injection, administered by a healthcare provider.

What are the warnings and precautions for Pemetrexed?

Caution should be exercised in patients with history of pleural effusion, kidney or liver disease, elderly, pregnancy and breastfeeding.

This medication is not advisable for children.

Avoid non-steroidal anti-inflammatory medications (NSAID) drugs, while taking this medication.

Avoid contact with people who have cold or flu like infections.

Monitor kidney function regularly while taking this medication.

What are the side effects of Pemetrexed?

  Body as whole: Easy bleeding, body aches, white patches inside the mouth or in the lip region, unusual weakness, fever, chills, rapid weight gain and swelling of the body part regions.
  Skin : Pale skin, skin rash and redness at the injection site.
  Genitourinary: Less urination frequency.
  Respiratory : Chest pain and trouble in breathing.
  Gastrointestinal: Nausea, vomiting, loss of appetite, diarrhea and constipation
  Blood: Anemia.
  Central Nervous System : Sleepiness, numbness, depression and tiredness.

What are the other precautions for Pemetrexed?

It may lead to poor blood clot.

What are the storage conditions for Pemetrexed?

Normally handled and stored by healthcare provider.

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