This medication is a modified enzyme, prescribed for severe combined immunodeficiency disease (SCID) in patients with adenosine deaminase (ADA) deficiency. It improves immune system function by correcting the levels of ADA in the body.
Contraindicated in patients with abnormal decrease in platelet counts, and hypersensitivity.
IM- The recommended dosing schedule is 10 U/kg for the first dose, 15 U/kg for the second dose, and 20 U/kg for the third dose. Maintenance: 20 U/kg per week.
It comes as a solution for injection to be administered by a healthcare provider into a large muscle.
• Caution should be exercised in patients with history of bleeding problem, any allergy, during pregnancy and breastfeeding.
• Avoid using contaminated solution of this medication.
• Blood :
Anemia and decrease in platelets.
• Skin : Injection site redness, hives and rash.
Avoid excess dosage.
Store it in refrigerator (2 to 8°C). Do not freeze it.
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