Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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General Information on Nortriptyline

Generic Name : Nortriptyline

Pronunciation : nor trip' ti leen

Latest prescription information about Nortriptyline. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.0 | Therapeutic Classification : Psychotherapeutics

Trade Names/Brand Names of Nortriptyline

Why is Nortriptyline Prescribed? (Indications)

This medication is an antidepressant, prescribed for depression. It increases the amounts of certain natural substances in the brain that are needed to maintain mental balance.

When should Nortriptyline not to be taken? (Contraindications)

Contraindicated in patients with recent heart attack, who are taking or have taken monoamine oxidase inhibitors within 14 days, linezolid or intravenous methylene blue and hypersensitivity.

What is the dosage of Nortriptyline?

Adult: PO- The recommended dose is 75-100 mg/day in 3-4 divided doses. Severe: upto 150 mg/day.

How should Nortriptyline be taken?

It comes as a capsule and tablet to take by mouth, with or without food.

What are the warnings and precautions for Nortriptyline?

• Caution should be exercised in patients with history of increased eye pressure, enlarged prostate, difficulty in urinating, sugar, seizures, mental illness, overactive thyroid, liver, kidney, or heart disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness, or blurred vision, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Do not become overheated; otherwise heatstroke may occur.

• Avoid exposure to sunlight.

What are the side effects of Nortriptyline?

•   Heart : Low or high blood pressure, fast heart rate, palpitations, heart attack, abnormal heart rhythm, heart block and stroke.
•   Central Nervous System : Numbness, tingling, incoordination, tremor, seizures, alteration in EEG patterns, hallucinations, disorientation, delusions, anxiety, restlessness, agitation and sleeplessness.
•   Eye and ENT : Dry mouth, blurred vision, vision disturbances, dilatation of pupil and ringing in the ear.
•   Allergic reactions : Skin rash, hives, itching, sensitivity to light, swelling in the face and tongue and fever.
•   Blood : Bone marrow depression and bruising.
•   Gastrointestinal : Nausea, vomiting, loss of appetite, stomach distress, diarrhea, peculiar taste, mouth ulcer, abdominal cramps and black-tongue.
•   Genitourinary : Breast enlargement in male, spontaneous milk secretion, increased or decreased sexual ativities, impotence. urinary retention and delayed urination.
•   Miscellaneous : Jaundice, altered liver function, weight gain or loss, flushing, urinary frequency, drowsiness, dizziness, weakness, fatigue, headache and hair loss.

What are the other precautions for Nortriptyline?

Avoid excess dosage.

What are the storage conditions for Nortriptyline?

Store it at controlled room temperature (20° to 25°C).

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