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General Information on Morphine Sulfate and Naltrexone Hydrochloride

Generic Name : Morphine Sulfate and Naltrexone Hydrochloride

Pronunciation : MORE-feen-nal-TREX-ohn

Latest prescription information about Morphine Sulfate and Naltrexone Hydrochloride. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y45 | Therapeutic Classification : Analgesics

Trade Names/Brand Names of Morphine Sulfate and Naltrexone Hydrochloride

International- Embeda.

Why is Morphine Sulfate and Naltrexone Hydrochloride Prescribed? (Indications)

This combination medication contains a narcotic analgesic and antagonist, prescribed for moderate to severe pain when a continuous opioid analgesic is needed. 

When should Morphine Sulfate and Naltrexone Hydrochloride not to be taken? (Contraindications)

Contraindicated in patients with severe lung disease, asthma, paralytic ileus, and hypersensitivity.

What is the dosage of Morphine Sulfate and Naltrexone Hydrochloride?

Dose is based on patient’s condition and response to the medication.
For Opioid- Tolerant Patients - PO- The recommended dose is 100mg/4mg/day.

How should Morphine Sulfate and Naltrexone Hydrochloride be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Morphine Sulfate and Naltrexone Hydrochloride?

• Caution should be exercised in patients with history of heart, liver or kidney disease, low blood pressure, asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, underactive thyroid, Addison disease, curvature of the spine, gallbladder problems, trouble in urinating, enlarged prostate, stomach or bowel problems, undergone stomach or bowel surgery, dehydration, weakness, head injury, who are taking other medications, any allergy, during pregnancy and breastfeeding.

• It may cause dizziness or drowsiness, do not drive a car or operate machinery and sit down or get up slowly while taking this medication.

• Avoid alcohol consumption.

What are the side effects of Morphine Sulfate and Naltrexone Hydrochloride?

•   Most Common : Drowsiness, dizziness, constipation and nausea.
•   Gastrointestinal: Abdominal pain, constipation, diarrhea, dry mouth, flatulence, stomach discomfort and vomiting.
•   General : Chills, swelling in the extremities, fatigue and irritability.
•   Metabolic : Loss of appetite.
•   Musculoskeletal : Joint pain and muscle spasm.
•   Central Nervous System : Dizziness, headache, sleeplessness, tremor, anxiety and depression.
•   Skin : Itching.
•   Heart : Flushing.

What are the other precautions for Morphine Sulfate and Naltrexone Hydrochloride?

Avoid excess dosage.

What are the storage conditions for Morphine Sulfate and Naltrexone Hydrochloride?

Store it at controlled room temperature (25°C).


Schedule : X

Narcotic and Psychotropic drugs which cannot be sold without the prescription of a Registered Medical Practitioner.
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