This combination medication contains a narcotic analgesic and antagonist, prescribed for moderate to severe pain when a continuous opioid analgesic is needed.
Contraindicated in patients with severe lung disease, asthma, paralytic ileus, and hypersensitivity.
Dose is based on patients condition and response to the medication.
For Opioid- Tolerant Patients - PO- The recommended dose is 100mg/4mg/day.
It comes as a capsule to take by mouth, with or without food.
Caution should be exercised in patients with history of heart, liver or kidney disease, low blood pressure, asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, underactive thyroid, Addison disease, curvature of the spine, gallbladder problems, trouble in urinating, enlarged prostate, stomach or bowel problems, undergone stomach or bowel surgery, dehydration, weakness, head injury, who are taking other medications, any allergy, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery and sit down or get up slowly while taking this medication.
Avoid alcohol consumption.
Most Common :
Drowsiness, dizziness, constipation and nausea.
Gastrointestinal: Abdominal pain, constipation, diarrhea, dry mouth, flatulence, stomach discomfort and vomiting.
General : Chills, swelling in the extremities, fatigue and irritability.
Metabolic : Loss of appetite.
Musculoskeletal : Joint pain and muscle spasm.
Central Nervous System : Dizziness, headache, sleeplessness, tremor, anxiety and depression.
Skin : Itching.
Heart : Flushing.
Avoid excess dosage.
Store it at controlled room temperature (25°C).
Subscribe to our Free Newsletters!