Milrinone - Indications, Dosage, Side Effects and Precautions

Last Updated on August 11, 2022
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Information about Milrinone

Generic Name : Milrinone
Up-to-date prescription details regarding Milrinone are provided here.
Pronunciation : MILL-ri-none
Learn the correct pronunciation of the Milrinone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y52 | Therapeutic Classification : Cardiovascular Agents

Trade Names/Brand Names of Milrinone

India : 

International : 


Why is Milrinone Prescribed? (Indications)

This medication is a phosphodiesterase 3 inhibitor, prescribed for acute decompensated heart failure (ADHF) (serious cause of acute respiratory distress).  It increases the pumping strength of the heart.


When should Milrinone not be taken? (Contraindications)

Contraindicated in patients with recent heart attack and hypersensitivity.

What is the dosage of Milrinone?

Adult: IV- Loading dose: 50 mcg/kg then continuous maintenance infusion of 0.375-0.75 mcg/kg/min. Adjust according to response. Max:1.13 mcg/kg/day.

How should Milrinone be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Milrinone?

• Caution should be exercised in patients with history of heart valve disease, irregular heartbeat, mineral imbalance, other heart diseases, kidney disease, any allergy, during pregnancy and breastfeeding.

It may cause dizziness or lightheadedness, do not drive a car or operate machinery while taking this medication.

Avoid alcohol consumption.

What are the side effects of Milrinone?

  This medication is generally well tolerated.
  Heart: Fast heart rate, abnormal/irregular heart beat, low blood pressure and chest pain.
  Central Nervous System: Headache.
  Miscellaneous: Decreased potassium level in blood, tremor and decreased platelet count.

What are the other precautions for Milrinone?

Avoid excess dosage.

What are the storage conditions for Milrinone?

Store it at room temperature (25C).

Last Updated : August 11, 2022

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