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Meropenem - Indications, Dosage, Side Effects and Precautions

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Information about Meropenem

Generic Name : Meropenem
Pronunciation : MER-oh-PEN-em
Latest prescription information about Meropenem. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y40.9 | Therapeutic Classification : Antibiotics
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Trade Names/Brand Names of Meropenem

India : 

More...

International : 

Merrem IV
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Why is Meropenem Prescribed? (Indications)

This medication is a carbapenem antibiotic, prescribed for bacterial infections like skin and skin structure infections, bacterial meningitis, serious nosocomial infections like septicaemia, febrile neutropenia, intraabdominal and pelvic infections. The medication inhibits cell wall synthesis in bacteria, and thereby leading to cell death. 

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When should Meropenem not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Meropenem?

IV- The recommended dose is 0.5 gm to 2 gm (10 to 40mg/kg) by slow infusion, 3 times per day.

How should Meropenem be taken?

It comes as a solution for injection, administered by a healthcare provider, into the vein.

What are the warnings and precautions for Meropenem?

• Caution needed for patients with history of hypersensitivity to carbapenem, pencillin or other beta-lactam antibiotics; infants <3 months; kidney malfunction, neurological disorders, pregnancy, and breastfeeding.

• Not recommended for use in MRSA (Methicillin-resistant Staphylococcus aureus) infections.

What are the side effects of Meropenem?

  Body as a Whole: Pain, abdominal pain, chest pain, fever, back pain, abdominal enlargement, chills and pelvic pain.
  Heart: Heart failure, heart arrest, fast/slow heart rate, high/low blood pressure, heart attack, blood clot in lungs and fainting.
  Gastrointestinal: Oral infection, loss of appetite, indigestion and intestinal obstruction.
  Blood: Anemia and increased blood volume.
  Metabolic: Peripheral edema and poor oxygen supply.
  Central Nervous System : Sleeplessness, agitation, confusion, dizziness, seizure, tingling, hallucinations, drowsiness, anxiety, depression and weakness.
  Respiratory : Respiratory disorder, difficulty in breathing, wheezing, pleural effusion, asthma, cough increased and lung swelling.
  Skin : Hives, sweating and skin ulcer.
  Genitourinary: Painful urination, kidney failure, vaginal infection and urinary incontinence.
  Liver: Jaundice and liver failure.
  Potentially Fatal: Anaphylaxis and Stevens-Johnsons sydrome.

What are the other precautions for Meropenem?

Long term or repeated use of this medication may cause secondary infection.

What are the storage conditions for Meropenem?

Injection: Once reconstituted, up to 2 hour at room temperature (15-25�C) or up to 12 hour at refrigerator (4�C).

Last Updated : Jun 2018

Meropenem: Drug to Treat Meningitis, Pneumonia, Sepsis and Other Bacterial Infections




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Comments

Maqbool1660, India

Rate of morepenium 1g , 500gm and Piperacillin / Tazobactam 1000 vial ?

kk2003, India

Whether injection Meropenem can be prescribed for patient admitted with Febrile Illness with fever 101F.

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