This medication is a HMG-CoA reductase inhibitor, prescribed for high cholesterol. It reduces the production of certain fatty substances in the body.
Contraindicated in patients with liver disease, elevated liver enzymes level, pregnancy, lactation and hypersensitivity.
It should not be co-administered with strong CYP3A4 inhibitors.
PO- The recommended dose range is 10-80 mg daily at bedtime.
It comes as a tablet to take by mouth, with food.
• Caution should be exercised in patients with history of liver disease, alcoholism, who had an organ transplant or surgery, any allergy, who are taking other medications, elderly and children.
• It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
• Avoid alcohol consumption.
• Monitor blood cholesterol level, liver function tests and creatine phosphokinase (CPK) blood levels regularly while taking this medication.
• Body As a Whole :
♦ • Gastrointestinal : Abdominal pain, non- fatal liver failure, constipation, diarrhea, indigestion, flatulence and nausea.
♦ • Musculoskeletal : Muscle cramps, muscle pain, Immune-Mediated Necrotizing Myopathy (IMNM).
♦ • Central Nervous System : Dizziness, cognitive impairment (e.g., memory loss, forgetfulness, amnesia, memory impairment, confusion) and headache.
• Skin : Rash.
• Special Senses : Blurred vision.
Avoid excess dosage.
Store it at room temperature (20-25°C). Store this medication away from light and out the reach of children.
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