General Information on Leuprolide
Generic Name : Leuprolide
Pronunciation : loo-PROL-lide
Latest prescription information about Leuprolide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Miscellaneous Endocrine Agents
Trade Names/Brand Names of Leuprolide
Lupron Depot, Eligard, Viadur
Why is Leuprolide Prescribed? (Indications)
This medication is a gonadotropin-releasing hormone (GnRH) agonist (hormonal chemotherapy), prescribed for prostate cancer, endometriosis, uterine fibroids, and central precocious puberty.
It decreases levels of certain hormones in the body.
When should Leuprolide not be taken? (Contraindications)
Contraindicated in pregnant women and patients with known hypersensitivity.
What is the dosage of Leuprolide?
SC- The recommended dose is 1 mg/day (0.2 ml or 20 unit mark) administered as a single dose.
How should Leuprolide be taken?
It comes as a solution for injection to be administered by a healthcare provider under the skin.
What are the warnings and precautions for Leuprolide?
• Caution should be exercised in patients with history of sugar, high blood sugar, urinary problems, spinal cord problems, heart disease, stroke, weak bones, osteoporosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• It may decrease certain hormone levels, they may cause severe side effects such as breast size changes, breast soreness or tenderness, testicular changes, irregular periods, decreased sexual ability, hot flashes. If it is so consult with your doctor.
• Patient may develop with increased risk of bone weakness, sugar; if you experience with unusual pain or tiredness consult with your doctor.
• Monitor blood testosterone levels, prostate-specific antigen (PSA), hemoglobin, blood glucose and bone density regularly while taking this medication.
What are the side effects of Leuprolide?
• Heart :
Heart failure, ECG changes, high blood pressure, murmur, inflammation of blood vessels, fluid accumulation and swelling.
• Gastrointestinal :
Loss of appetite, constipation, nausea and vomiting.
• Genitourinary :
Decreased testicular size, breast enlargement in male, breast tenderness or pain, hot flashes, impotence urine frequency/urgency, blood in urine and urinary tract infection.
• Blood :
• Musculoskeletal :
• Central Nervous System :
Dizziness, lightheadedness, general pain, headache, convulsions and sleep disorders.
• Respiratory :
Difficulty in breathing and nasal congestion.
• Skin :
• Miscellaneous :
What are the other precautions for Leuprolide?
It should not be used in children.
Avoid excess dosage.
What are the storage conditions for Leuprolide?
Store it at room temperature. Keep away from children.