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Luprofact is a gonadotropin-releasing hormone (GnRH) agonist (hormonal chemotherapy), prescribed for prostate cancer, endometriosis, uterine fibroids, and central precocious puberty.  It decreases levels of certain hormones in the body.

Drug information on Luprofact (Leuprolide) from Zydus Cadila Healthcare Ltd. (Biogen)


Zydus Cadila Healthcare Ltd. (Biogen)
Generic : Leuprolide
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Medical Condition(s) for which Luprofact may be prescribed

Side effects of Luprofact

   Heart : Heart failure, ECG changes, high blood pressure, murmur, inflammation of blood vessels, fluid accumulation and swelling.

   Gastrointestinal : Loss of appetite, constipation, nausea and vomiting.

   Genitourinary : Decreased testicular size, breast enlargement in male, breast tenderness or pain, hot flashes, impotence urine frequency/urgency, blood in urine and urinary tract infection.

   Blood : Anemia.

   Musculoskeletal : Bone/muscle pain.

   Central Nervous System : Dizziness, lightheadedness, general pain, headache, convulsions and sleep disorders.

   Respiratory : Difficulty in breathing and nasal congestion.

   Skin : Skin inflammation.

   Miscellaneous : Weakness.

Dosage & When it is to be taken (Indications)

SC- The recommended dose is 1 mg/day (0.2 ml or 20 unit mark) administered as a single dose.

How to use Luprofact?

It comes as a solution for injection to be administered by a healthcare provider under the skin.

When is Luprofact not to be taken? (Contraindications)

Contraindicated in pregnant women and patients with known hypersensitivity.

Warnings and Precautions for Luprofact

Caution should be exercised in patients with history of sugar, high blood sugar, urinary problems, spinal cord problems, heart disease, stroke, weak bones, osteoporosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may decrease certain hormone levels, they may cause severe side effects such as breast size changes, breast soreness or tenderness, testicular changes, irregular periods, decreased ability, hot flashes. If it is so consult with your doctor.

• Patient may develop with increased risk of bone weakness, sugar; if you experience with unusual pain or tiredness consult with your doctor.

• Monitor blood testosterone levels, prostate-specific antigen (PSA), hemoglobin, blood glucose and bone density regularly while taking this medication.

Other Precautions for Luprofact

It should not be used in children.
Avoid excess dosage.

Storage Conditions for Luprofact

Store it at room temperature. Keep away from children.

♦ Safety Labeling Changes Approved By FDA

Disclaimer : The Price of the drugs indicated above may not match the actual price at which they are sold. Prices can change depending on many factors, including GST. These are only approximate indicative prices of the drug.
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Substitutes for Luprofact

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