Dhanalakshmi Chinnuswamy
Medically Reviewed by The Medindia Medical Review Team on Jan 11, 2013
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General Information on Lamivudine- Zidovudine

Generic Name : Lamivudine- Zidovudine

Pronunciation : la mi' vyoo deen- zye doe' vyoo deen

Latest prescription information about Lamivudine- Zidovudine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.5 | Therapeutic Classification : Antiretroviral Agents

Trade Names/Brand Names of Lamivudine- Zidovudine

India- Combivir, Cytocom, Cytocom-E, Cytocom-N, Duovir, Duovir-E, Duovir-N, Lamda-Z, Lami Plus, Lamsyn-Z, Lamuzid, Lazid Tab, Lazid-E, Lazid-N, Virocmb-E, Virocomb, Virocomb-N, Zidolam, Zidolam-N, Zvd Plus.
International- Combivir.

Why is Lamivudine- Zidovudine Prescribed? (Indications)

This combination medication contains antivirals, prescribed for HIV infection. It works by decreasing the amount of HIV in the blood.

When should Lamivudine- Zidovudine not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Lamivudine- Zidovudine?

Each film-coated tablet contains 150 mg of lamivudine, 300 mg of zidovudine.
For patients weighing greater than or equal to 30 kg the recommended oral dose is 1 tablet.

How should Lamivudine- Zidovudine be taken?

It comes as a tablet to take by mouth, with or without food.

What are the warnings and precautions for Lamivudine- Zidovudine?

Caution should be exercised in patients with history of kidney or liver impairment, bone marrow disorder, abnormal blood cell counts, nerve or muscle problems, weighing less than 66 lbs (30 kg), any allergy, who are taking other medications, children, during pregnancy and breastfeeding.

It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

It does not stop spread of HIV infection to others; avoid sexual contact, sharing of needles, injection supplies, or items like toothbrushes or razors during treatment period.

Monitor complete blood cell count, liver and kidney functions regularly while taking this medication.

What are the side effects of Lamivudine- Zidovudine?

   Body as a Whole : Headache, uneasiness, fatigue, fever or chills.
   Gastrointestinal : Nausea, diarrhea, vomiting, loss of appetite, abdominal pain, abdominal cramps, indigestion.
   Central Nervous System : Nerve disease, sleeplessness, dizziness, and depression.
   Respiratory : Nose irritation, cough.
   Skin : Rash.
   Musculoskeletal : Muscle pain, joint pain.

What are the other precautions for Lamivudine- Zidovudine?

Avoid excess dosage.

What are the storage conditions for Lamivudine- Zidovudine?

Store between 2 and 30C.

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