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Hydrochlorothiazide - Indications, Dosage, Side Effects and Precautions

Hydrochlorothiazide Medication Information

Learn everything you need to know about Hydrochlorothiazide-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Hydrochlorothiazide brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Hydrochlorothiazide
Pronunciation : hye droe klor oh thye' a zide
ICD Code : Y54.5 Therapeutic Classification : Diuretics

Brand Names or Trade Names of Hydrochlorothiazide

India :

International :


HydroDIURIL, Microzide

Why is Hydrochlorothiazide Prescribed? (Indications)

This medication is a thiazide diuretic, prescribed for high blood pressure (hypertension) and edema. It helps the kidneys to remove fluid from the body.

When should Hydrochlorothiazide not be taken? (Contraindications)

Contraindicated in patients with urination problem, who are taking potassium-sparing agents and hypersensitivity.

What is the dosage of Hydrochlorothiazide?

Adult- HTN- The recommended dose is 12.5 to 50 mg once daily.
Edema- The recommended dose is 25-100 mg once daily or in divided doses.

How should Hydrochlorothiazide be taken?

It comes as a tablet and liquid to take by mouth, with food.

What are the warnings and precautions for Hydrochlorothiazide?

• Caution should be exercised in patients with history of diabetes, gout, asthma or kidney, liver, thyroid disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• It may raise blood sugar level, monitor sugar level regularly while taking this medication.

• Monitor kidney function, blood pressure and electrolyte levels while taking this medication.

What are the side effects of Hydrochlorothiazide?

Body as a whole - Weakness.
Hypersensitivity - Rash, hives, shock and photosensitivity.
Heart - Abnormal heart rhythm and low blood pressure.
Metabolic - Increased sugar.
Gastrointestinal - Jaundice and/or liver enzyme abnormalities, nausea, vomiting, diarrhea, constipation and abdominal pain.
Genitourinary - Kidney failure.
Blood - Decrease in white blood cells and anemia.
Musculoskeletal - Muscle cramps.
Central Nervous System - Weakness, fatigue, dizziness, headache, dry mouth, tingling and vertigo.
Miscellaneous - Impotence.
Eye - Blurred vision.
Respiratory - Lung swelling and respiratory distress.
Skin - Cell death.

What are the other precautions for Hydrochlorothiazide?

Avoid exposure to sunlight.

What are the storage conditions for Hydrochlorothiazide?

Store it at controlled room temperature (20° to 25°C).

Hydrochlorothiazide : Frequently Asked Questions

Q: Does Hydrochlorothiazide cause frequent urination?

A: Hydrochlorothiazide, a water pill, causes frequent urination. When prescribed at bedtime, it is better to take this medication in the early evening to avoid waking up frequently to urinate (1 Trusted Source
Hydrochlorothiazide

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).

Q: Is long-term use of Hydrochlorothiazide safe?

A: Hydrochlorothiazide is relatively safe and intended for long-term use. Sudden withdrawal from this medication can cause serious, life-threatening heart problems (2 Trusted Source
Hydrochlorothiazide

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).

Q: Is it safe to drink coffee while taking Hydrochlorothiazide?

A: It is best to avoid drinking coffee while taking hydrochlorothiazide. Caffeine can raise blood pressure, and when taken with water pills like hydrochlorothiazide, it can lead to serum potassium depletion (low serum potassium levels) (3 Trusted Source
The Effect of Coffee on Pharmacokinetic Properties of Drugs : A Review

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).

Q: Does Hydrochlorothiazide affect your skin?

A: Hydrochlorothiazide has photosensitive properties, so it is best to avoid sunlight while taking this medication. It is associated with skin cancer and can cause skin problems such as dryness and rashes (4 Trusted Source
Reviewing the effects of thiazide and thiazide-like diuretics as photosensitizing drugs on the risk of skin cancer

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). 

Q: Is Hydrochlorothiazide a high-risk drug?

A: Hydrochlorothiazide is a thiazide-type diuretic that has been used to treat hypertension globally and is a relatively safe drug (5 Trusted Source
Hydrochlorothiazide

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).



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