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Glucarpidase Injection - Indications, Dosage, Side Effects and Precautions

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Information about Glucarpidase Injection

Generic Name : Glucarpidase Injection
Up-to-date prescription details regarding Glucarpidase Injection are provided here.

Understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y43.6 Therapeutic Classification : Enzymes

Trade Names/Brand Names of Glucarpidase Injection

International :


Voraxaze

Why is Glucarpidase Injection Prescribed? (Indications)

This medication is a carboxypeptidase enzyme, prescribed for reducing methotrexate toxic level in kidney failure patients. It converts methotrexate into an inactive substance.

When should Glucarpidase Injection not be taken? (Contraindications)

None.

What is the dosage of Glucarpidase Injection?

IV- The recommended dose is 50 Units per kg as a single dose.

How should Glucarpidase Injection be taken?

It comes as a powder (diluted with fluid) for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Glucarpidase Injection?

• Caution should be exercised in patients with history of liver or kidney impairment, any allergy, elderly, children, during pregnancy and breastfeeding.

What are the side effects of Glucarpidase Injection?

Tingling, flushing, nausea, vomiting, headache, low blood pressure, blurred vision, diarrhea, hypersensitivity, high blood pressure, rash, throat irritation.

What are the other precautions for Glucarpidase Injection?

Avoid excess dosage.

What are the storage conditions for Glucarpidase Injection?

• Store in a refrigerator at a controlled temperature between 2°C and 8°C.
• Vials should not be frozen
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