This medication is an ergot alkaloid, prescribed for migraine headache. It causes vasoconstriction (narrowing of blood vessels).
Contraindicated in patients with coronary heart disease, high blood pressure, liver or kidney problems or severe infection, blood vessels problem, who are taking antifungal medications, HIV protease inhibitors, macrolide antibiotic medications, during pregnancy, labor and hypersensitivity.
PO-Sublingual and rectal: The recommended initial dose is 2 mg ergotamine with fixed combination with caffeine. Maximum: 10 mg/week.
It comes as a tablet to take by mouth (to be placed under the tongue) and as a suppository to insert rectally.
• Caution should be exercised in patients with history of blood problems, stroke, anxiety, sleeping problems or heart problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Avoid exposure to cold.
• Heart :
Bluish, absence of pulse, cold extremities, cell death, heart failure, pain, EKG changes, muscle pain, fast/slow heart rate and high blood pressure.
• Gastrointestinal : Nausea and vomiting.
• Central Nervous System : Tingling, numbness, weakness and unsteadiness.
• Allergic Reactions : Localized swelling and itching.
Avoid excess dosage.
Store at controlled room temperature 15° -30° C
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