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General Information on Entacapone

Generic Name : Entacapone

Pronunciation : en-TAK-a-pone

Latest prescription information about Entacapone. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y46.7 | Therapeutic Classification : Antiparkinson Agents

Trade Names/Brand Names of Entacapone

India : 

International : 

Comtan

Why is Entacapone Prescribed? (Indications)

This medication is catechol-o-methyltransferase (COMT) inhibitor, used as an adjunct to levodopa/carbidopa to treat patients with idiopathic Parkinson‘s disease. It is used during the later stages when the patient does not respond well to levodopa/carbidopa. It increases the levels of levodopa/carbidopa in the brain, enhancing its effectiveness. 

When should Entacapone not to be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Entacapone?

PO: The recommended dose is 200 mg with each levodopa/carbidopa up to a maximum of 1600 mg/day.

How should Entacapone be taken?

It comes as a tablet to take by mouth.

What are the warnings and precautions for Entacapone?

• It may cause dizziness, lightheadedness, or fainting; do not drive a car or operate machinery, while taking this medication.

• Avoid alcohol consumption.

• It may lead to an increase in involuntary movements.

• Caution needed during pregnancy and breastfeeding.

What are the side effects of Entacapone?

  Most Common: Diarrhea, movement disorder, nausea, abdominal pain.
  Skin : Sweating increased
  Central Nervous System : Involuntary movements, increased or decreased movements, dizziness, anxiety, drowsiness, agitation, and worsening of condition.
  ENT: Taste perversion
  Gastrointestinal : Nausea, diarrhea, abdominal pain, constipation, vomiting, dry mouth, indigestion, flatulence, gastritis.
  Respiratory: Difficulty in breathing.
  Blood: Easy bruising
  Genitourinary: Urine discoloration
  Body as a whole: Back pain, fatigue, weakness
  Miscellaneous: Bacterial infection.

What are the other precautions for Entacapone?

Stop this medication if unwanted symptoms developed.

What are the storage conditions for Entacapone?

Store it at room temperature and in airtight container. Keep away from children

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