Drotrecogin Alfa Medication Information

Learn everything you need to know about Drotrecogin Alfa-pronunciation, uses, dosage guidelines, indications, and when to take or avoid it.

Get up-to-date information on side effects, precautions, warnings, and proper storage to ensure safe usage.

Explore Drotrecogin Alfa brand names commonly used in India and internationally, along with detailed pricing information. Consult your healthcare provider for tailored medical advice.

Generic Name : Drotrecogin Alfa

Pronunciation : droe-tre-KOE-gin AL-fa

ICD Code : Y44.2 Therapeutic Classification : Anticoagulants / Antithrombotics

Brand Names or Trade Names of Drotrecogin Alfa

Xigris | Xigris (20 mg)

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International :

Xigris Vial

Why is Drotrecogin Alfa Prescribed? (Indications)

This medication is a recombinant form of human activated protein C, prescribed for life-threatening bacterial infections like severe sepsis (sepsis combined with organ malfunction).

When should Drotrecogin Alfa not be taken? (Contraindications)

Contraindicated in patients with high risk of intrinsic bleeding, stroke, epidural catheter, trauma, brain tumor and known hypersensitivity.

What is the dosage of Drotrecogin Alfa?

Adults-Infuse intravenously at 24 mcg/kg/hr (based on actual body weight) for a total duration of 96 hours.

How should Drotrecogin Alfa be taken?

It comes as a solution to be injected by a doctor or hospital staff.

What are the warnings and precautions for Drotrecogin Alfa?

•It may cause severe bleeding, lie down in the bed during the treatment.

• Monitor complete blood count, liver and kidney functions regularly while taking this medication.

• Caution needed for patients with history of kidney disease, liver disease, HIV, organ transplants, stroke, head or spinal surgeries, ulcers, low platelet count, pregnancy, breastfeeding and any form of allergies.

What are the side effects of Drotrecogin Alfa?

Most Common- High risk of bleeding in gastrointestinal tract, abdominal tract, brain (hemorrhagic stroke), skin and chest cavity.
Blood- Decrease in the platelet count.
Genitourinary- Renal failure, blood in urine.