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Diphenylpyraline - Indications, Dosage, Side Effects and Precautions

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Diphenylpyraline Medication Information

Get detailed information on Diphenylpyraline, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

The updated prescription information on Diphenylpyraline provides an overview of possible side effects, precautions, warnings, and storage tips.

You'll also find brand names used in india and internationally, along with pricing details. For further clarification, consult your healthcare provider.

Generic Name : Diphenylpyraline
Pronunciation : Di-phe-nyl-pyra-line
Therapeutic Classification : Antihistamines

Trade Names/Brand Names of Diphenylpyraline

India :


Solphyllex, Actophlem Cough Syrup

Overview of Diphenylpyraline

• Diphenylpyraline is used for the treatment of hay fever, rhinitis, itchy skin disorders and other conditions.

Why is Diphenylpyraline Prescribed? (Indications)

Diphenylpyraline is an antihistamine.
It is used for the treatment of hay fever, rhinitis, itchy skin and other allergies.

When should Diphenylpyraline not be taken? (Contraindications)

Diphenylpyraline should not be used in patients with:

• Allergy to diphenylpyraline
• Severe liver disease
• Angle-closure glaucoma
Enlargement of the prostate
• Seizures
• It should also not be used in infants, the elderly, and during pregnancy and breastfeeding.

What is the dosage of Diphenylpyraline?

• The recommended dose of the drug is a maximum of 6 mg/day in three to four divided doses.

How should Diphenylpyraline be taken?

• This drug should be taken in three to four divided doses orally.

What are the warnings and precautions for Diphenylpyraline?

• Avoid alcohol intake with the medication.

What are the side effects of Diphenylpyraline?

Nervous system: Sedation, inability to concentrate, diminished alertness, rarely seizures
Digestive tract: Dry mouth, constipation
Urinary tract: Urinary retention
Eyes: Blurring of vision, dry eyes, worsening of glaucoma
Heart: Palpitations, abnormal heart rhythms
Others: Allergic reactions, ringing in the ears

What are the other precautions for Diphenylpyraline?

• Do not use the drug if you need to drive or use heavy machinery.

What are the Drug Interactions of Diphenylpyraline?

• The drug interacts with barbiturates, hypnotics, anxiolytics, sedatives and antipsychotics as it increases the sedation caused by the drugs.
• It can increase the anticholinergic effects of drugs like atropine, tricyclic antidepressants resulting in side effects like dry mouth, blurring of vision, constipation and urinary retention.
• It should not be used with betahistine since it blocks the effects of betahistine.
• It should be avoided with bupropion due to an increased risk for seizures.
• It should be avoided with drugs that can affect the heart rhythm like mefloquine.

What are the storage conditions for Diphenylpyraline?

• It should be stored at room temperature.
• Keep it away from the reach of children.

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