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Mefloquine - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Mefloquine

Generic Name : Mefloquine
Pronunciation : meff-lo-kwin
Latest prescription information about Mefloquine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.2 | Therapeutic Classification : Anti- Malarials
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Trade Names/Brand Names of Mefloquine

India : 

International : 

Lariam
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Why is Mefloquine Prescribed? (Indications)

This medication is an antimalarial agent, prescribed for malaria.  It works by killing the organisms that cause malaria.

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When should Mefloquine not be taken? (Contraindications)

Contraindicated in patients with depression, anxiety disorder, or psychiatric disorders and hypersensitivity.

What is the dosage of Mefloquine?

PO- The recommended dose is 1250 mg to be given as a single dose.

How should Mefloquine be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Mefloquine?

• Caution should be exercised in patients with history of seizures, heart disease, blood clotting problems, liver impairment, sugar, depression, suicidal thoughts, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause drowsiness, dizziness, lightheadedness, do not drive a car or operate machinery while taking this medication.

• Protect yourself from mosquito bites; otherwise can get infected with malaria.

• Avoid live vaccinations.

What are the side effects of Mefloquine?

   Most Common : Dizziness, muscle pain, nausea, fever, headache, vomiting, chills, diarrhea, skin rash, abdominal pain, fatigue, loss of appetite and ringing in the ear.
   Heart : Circulatory disturbances, chest pain, fast heart rate, palpitations and irregular pulse.
   Skin : Rash, redness, hives, itching, swelling in the leg, hair loss and Stevens-Johnson syndrome.
   Musculoskeletal : Muscle weakness, muscle cramps and muscle/joint pain.
   Respiratory : Difficulty in breathing.
   Miscellaneous : Visual disturbances, hearing impairment, weakness, uneasiness, fatigue, fever, increased sweating, chills, indigestion and loss of appetite.

What are the other precautions for Mefloquine?

Avoid excess dosage.

What are the storage conditions for Mefloquine?

Store it at room temperature (25°C).




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