This medication is prescribed for blood cancer(Chronic Myeloid Leukemia). It is a protein-tyrosinekinase inhibitor. It blocks the action of an abnormal protein that signals cancer cells to multiply.
Chronic Phase CML Adults-
Start with 100 mg orally once daily in the morning or evening. May increase dosage to 140 mg once daily in patients who do not achieve a hematologic or cytogenetic response.
Accelerated Phase CML, Myeloid or Lymphoid Blast Phase CML, or Ph+ ALL Adults- Start with 140 mg once daily in the morning or evening. May escalate dosage to 180 mg once daily in patients who do not achieve a hematologic or cytogenetic response.
It comes as a tablet to take by mouth. It is usually taken twice a day, in the morning and evening, with or without food.
• Central Nervous System:
Headache, dizziness, confusion, depression, mood or mental changes, signs of bleeding in the brain, seizures.
• Heart: Chest pain, irregular heartbeat, shortness of breath.
• Gastrointestinal: Nausea, vomiting, sores in the mouth, severe or persistent diarrhea, blood in the vomit.
• Skin: Skin rash, peeling skin, red, swollen, or blistered skin.
• Miscellaneous: Muscle pain, tiredness, weight loss, change in the amount of urine, dry cough, fainting, irritation or, ringing in the ears.
Use with caution in patients receiving anticoagulants or medications that may inhibit platelet function.
Store at 25°C. Store it in an airtight container and keep away from children.