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Daptomycin - Indications, Dosage, Side Effects and Precautions

Written & Compiled by Anushta Chandrapalan, M.Sc  | Medically Reviewed by The Medindia Medical Review Team
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Information about Daptomycin

Generic Name : Daptomycin
Pronunciation : DAP-toe-MYE-sin
Latest prescription information about Daptomycin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y40.9 | Therapeutic Classification : Antibiotics
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Trade Names/Brand Names of Daptomycin

International- Cubicin.
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Why is Daptomycin Prescribed? (Indications)

This medication is an antibiotic, prescribed for serious infections. It works by killing the bacteria.
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When should Daptomycin not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Daptomycin?

Adult- IV- The recommended dose is 4 mg/kg in 0.9% sodium chloride injection once every 24 hours for 7 to 14 days.

How should Daptomycin be taken?

It comes as a powder for injection (diluted with fluid), to be administered by a healthcare provider.

What are the warnings and precautions for Daptomycin?

• Caution should be exercised in patients with history of muscle, nerve problems, liver, or kidney disease, bowel problems caused by antibiotic use, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Daptomycin?

   Gastrointestinal : Diarrhea.
   Central Nervous system: Headache and dizziness.
   Skin : Rash.
   Gastrointestinal : Abnormal liver function tests.
   Genitourinary : Urinary tract infections.
   Heart : Low blood pressure.
♦ •   Respiratory : Difficulty in breathing and Eosinophilic pneumonia.
   Body as a Whole : Fatigue, weakness, rigors, flushing and hypersensitivity

What are the other precautions for Daptomycin?

Avoid excess and long-term use of this medication.

What are the storage conditions for Daptomycin?

Store it in refrigerator (2 to 8C).



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