Colchicine - Indications, Dosage, Side Effects and Precautions


Information about Colchicine

Generic Name : Colchicine
Up-to-date prescription details regarding Colchicine are provided here.

Pronunciation : kol' chi seen

Learn the correct pronunciation of the Colchicine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Therapeutic Classification : Gout Therapy

Trade Names/Brand Names of Colchicine

India :

Why is Colchicine Prescribed? (Indications)

This medication is an anti-gout agent, prescribed for gout or gouty arthritis. This medication reduces swelling and pain.
The medication is also used to treat Familial Mediterranean fever (FMF) in adults and children aged above 4 years.
FMF is a genetic condition in which, the patient experiences recurrent episodes of accompanied by pain in the abdomen, chest, or joints.
 It stops the natural processes that cause swelling and other symptoms of gout or gouty arthritis.

When should Colchicine not be taken? (Contraindications)

Contraindicated in patients with severe gastrointestinal, liver, kidney and heart diseases and hypersensitivity.

What is the dosage of Colchicine?

For preventing gouty arthritis in adults and adolescents older than 16 years of age: one or two 0.6 mg tablets.
For treating Gout Flares: 1.2 mg followed by 0.6 mg (one tablet) one hour later
For FMF: 0.3 to 1.8 mg

How should Colchicine be taken?

It comes as a tablet or capsule to be taken by mouth with or without food.

What are the warnings and precautions for Colchicine?

• Caution should be exercised in patients with history of blood disorder, stomach or bowel problems, heart, liver or kidney problems, underwent dialysis, any allergy, who are taking other medications, elderly, children less than 4 years, during pregnancy and breast feeding.

• Avoid excess dosage.

• Avoid contact with people who have infections.

• It may reduce platelet counts; avoid injury or bruising.

• Monitor complete blood cell counts, kidney function and liver function regularly while taking this medication.

What are the side effects of Colchicine?

Severe effects - Bone marrow depression.
Gastrointestinal - Nausea, vomiting, diarrhea and stomach discomfort.
Blood - Decreased white blood cells.
Others - Rash, fever, sore throat and unusual bleeding or bruising.

What are the other precautions for Colchicine?

Avoid excess dosage.

What are the storage conditions for Colchicine?

Store it at room temperature and in an airtight container.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.