What is Rheumatoid Arthritis?
Rheumatoid arthritis can occur at any age, but is more common in middle age. Women are more prone to the disease than men.
The exact cause of rheumatoid arthritis is unknown. Infection, genes and hormonal changes may be linked to the disease.
Rheumatoid arthritis leads to pain, swelling, stiffness and loss of function in the joints. Being a systemic disease, it tends to affect other organs in the body as well.
Rheumatoid arthritis progresses in 3 stages:
- Stage 1- Swelling of the synovial lining; causing pain, warmth, stiffness, redness and swelling around the joint.
- Stage 2- Rapid division and growth of cells, or pannus; which causes the synovium to thicken.
- Stage 3- The inflamed cells release enzymes that might damage bone and cartilage; often causing the involved joint to lose its shape and alignment, causing more pain and loss of movement.
Rheumatoid arthritis requires lifelong treatment with medications, physical therapy, exercise, education and surgery. Early, aggressive treatment can delay joint destruction.
Latest Publications and Research on Rheumatoid ArthritisDevelopment of a multi-biomarker disease activity test for rheumatoid arthritis. - Published by PubMed
Novel risk factors for cardiovascular disease in rheumatoid arthritis. - Published by PubMed
A database for curating the associations between killer cell immunoglobulin-like receptors and diseases in worldwide populations. - Published by PubMed
The role of high mobility group box chromosomal protein 1 in rheumatoid arthritis. - Published by PubMed
A simple model that suggests possible cost savings when modified-release prednisone 5 mg/day is added to current treatment in patients with active rheumatoid arthritis. - Published by PubMed