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Clopidogrel - Indications, Dosage, Side Effects and Precautions

Last Updated on May 11, 2020
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Information about Clopidogrel

Generic Name : Clopidogrel
Pronunciation : kloe-PID-oh-grel
Latest prescription information about Clopidogrel. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y44.2 | Therapeutic Classification : Anticoagulants / Antithrombotics

Trade Names/Brand Names of Clopidogrel

India : 


International : 


Why is Clopidogrel Prescribed? (Indications)

This medication is an anti-platelet agent, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. This medication is prescribed either alone or with other medications for prevention or treatment of stroke and heart attack (which are usually caused by blood clots) in persons who are at high risk. 

When should Clopidogrel not be taken? (Contraindications)

Contraindicated to hypersensitivity, peptic ulcer or bleeding within the skull.

What is the dosage of Clopidogrel?

Oral- Prophylaxis of blood clot events- 75 mg once daily.
Acute coronary syndrome For ST-elevation myocardial infarction: with aspirin: 75 mg once daily.
For unstable angina, non-ST-elevation myocardial infarction: Initial: 300 mg loading dose, followed by 75 mg once daily (with aspirin 75-325 mg once daily).

How should Clopidogrel be taken?

It comes as a tablet to take by mouth. It is usually taken once a day with or without food.

What are the warnings and precautions for Clopidogrel?

• Caution needed for patients at risk of increased bleeding from trauma, surgery, or other pathological conditions; ulcer; liver and kidney impairment; history of bleeding or haemostatic disorders, pregnancy.

Avoid injury or bruising while taking this medication.

It may cause dizziness, avoid driving a car or operating machinery, or other unsafe tasks.

What are the side effects of Clopidogrel?

  Heart: Swelling, high blood pressure, inflammation of blood vessels.
  Central Nervous System: Headache, dizziness, depression, confusion.
  Skin: Rash, itching, severe allergic reactions (severe rash, itching, swelling, severe dizziness, trouble breathing) Stevens-Johnson syndrome, toxic epidermal necrolysis.
  Eye and ENT: Bleeding in retina, conjunctiva.
  Gastrointestinal: Abdominal pain, diarrhea, stomach upset, nausea, inflammation of colon (including ulcerative or lymphocytic), inflammation of pancreas, mouth ulcer, taste disorders.
  Genitourinary: Urinary tract infection, kidney disease, increased creatinine levels.
  Blood: Bruising, nose bleeds, anemia, bleeding (including intracranial, GI, and retroperitoneal hemorrhage), and decrease in platelets.
  Liver: Abnormality in liver enzymes, inflammation of liver.
  Metabolic: Increase in cholesterol.
  Musculoskeletal: Muscle pain, back pain, muscle weakness.
  Respiratory: Upper respiratory tract infection, difficulty in breathing, inflammation of bronchus, stuffy nose, coughing.
  Miscellaneous: Accidental injury, chest pain, influenza-like symptoms, fatigue, fainting, hypersensitivity reactions, serum sickness, bleeding of wounds.

What are the other precautions for Clopidogrel?

Do not change the dose or stop taking unless advised by health care provider.

What are the storage conditions for Clopidogrel?

Store at 25 C. Store it in an airtight container and keep away from children.
Last Updated : Apr 2018
Learn more about Clopidogrel's interaction with Food, Herbs and Alcohol

Clopidogrel: Antiplatelet Drug to Prevent Risk of Heart Disease and Stroke

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hdhawan, India

is clavix as 150 150/150 or 75/150

jbernard, Panama

My mother has been on Plavix for about 6 years now. What happens if she changes to a generic ?

prishanthini, India

ma dad using clopidogrel he had brain stem stroke .he s known case of hypertension always he s complaints of dizziness ...and also he s taking piracetam n idebenone ,,,,den digoxin for lv severe dys function

vijender65, India

should I stop taking ceruvin tab 75 as I want to get my aching tooth extracted by a dentist

abdulkader, India

I'm using clopidogrel from two years,is there any Medicine to prevent said effect, like increasing cerum creatinin

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