This medication is cephalosporin antibiotic, prescribed for certain bacterial infections. It kills sensitive bacteria.
Hypersensitivity to cephalosporins.
IV- UTI- The recommended dose is 0.5-1 g 12 hourly for 7-10 days.
Empirical therapy for febrile neutropenia- 2 g 8 hourly for 7 days or until resolution of neutropenia.
It comes as a solution for injection, administered by a healthcare provider either into a large muscle or vein over 30 minutes.
Caution should be exercised in patients with history of penicillin or cephalosporin allergy, gastro intestinal disease, especially colitis; lactation, pregnancy, seizures.
It may decrease prothrombin activity; monitor prothrombin time in patients with poor nutritional state, kidney or liver impairment and those on prolonged treatment.
Prolonged treatment may result in overgrowth of non-susceptible organisms, resulting in superinfection.
Consider the possibility of Clostridium difficile associated diarrhea in patients who present with diarrhea after treatment.
♦Patient may develop with increased risk of neurotoxicity.
Central Nervous System:
Gastrointestinal: Nausea, vomiting, diarrhea, inflammation of colon, including pseudomembranous colitis, oral candidiasis.
Skin: Rash, itching, hives.
Miscellaneous: Hypersensitivity, including, allergic reaction, toxic epidermal blistering, rash, inflammation or veins, pain or inflammation at injection site; fever.
In diabetes patients - it may cause the results of some tests for urine glucose to be wrong. Becareful while changing the dose of your diabetes medicine.
Injection: In dry state: Store at 2-25°C and protected from light. After reconstitution: This solution is stable for 24 hour at controlled room temperature (2-25°C) and for 7 days under refrigeration (2-8°C).
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