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General Information on Cefepime

Generic Name : Cefepime

Pronunciation : SEF-e-peem

Latest prescription information about Cefepime. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y40.1 | Therapeutic Classification : Antibiotics

Why is Cefepime Prescribed? (Indications)

This medication is cephalosporin antibiotic, prescribed for certain bacterial infections. It kills sensitive bacteria. 

When should Cefepime not to be taken? (Contraindications)

Hypersensitivity to cephalosporins.

What is the dosage of Cefepime?

IV- UTI- The recommended dose is 0.5-1 g 12 hourly for 7-10 days.
Empirical therapy for febrile neutropenia- 2 g 8 hourly for 7 days or until resolution of neutropenia.

How should Cefepime be taken?

It comes as a solution for injection, administered by a healthcare provider either into a large muscle or vein over 30 minutes.

What are the warnings and precautions for Cefepime?

• Caution should be exercised in patients with history of penicillin or cephalosporin allergy, gastro intestinal disease, especially colitis; lactation, pregnancy, seizures.

• It may decrease prothrombin activity; monitor prothrombin time in patients with poor nutritional state, kidney or liver impairment and those on prolonged treatment.

• Prolonged treatment may result in overgrowth of non-susceptible organisms, resulting in superinfection.

• Consider the possibility of Clostridium difficile associated diarrhea in patients who present with diarrhea after treatment.

Patient may develop with increased risk of neurotoxicity.

What are the side effects of Cefepime?

  Central Nervous System: Headache.
  Gastrointestinal: Nausea, vomiting, diarrhea, inflammation of colon, including pseudomembranous colitis, oral candidiasis.
  Skin: Rash, itching, hives.
  Miscellaneous: Hypersensitivity, including, allergic reaction, toxic epidermal blistering, rash, inflammation or veins, pain or inflammation at injection site; fever.

What are the other precautions for Cefepime?

In diabetes patients - it may cause the results of some tests for urine glucose to be wrong. Becareful while changing the dose of your diabetes medicine.

What are the storage conditions for Cefepime?

Injection: In dry state: Store at 2-25°C and protected from light. After reconstitution: This solution is stable for 24 hour at controlled room temperature (2-25°C) and for 7 days under refrigeration (2-8°C).

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