This medication is a protease inhibitor, prescribed for chronic hepatitis C. It decreases the amount of hepatitis C virus (HCV) in the body.
Contraindicated in pregnant women, co-administration with drugs highly dependent on CYP3A4/5, Adrenoreceptor antagonist, Anticonvulsants, Ergot derivatives, HMG-CoA reductase inhibitors, PDE5 enzyme Inhibitor, Sedative/Hypnotics, St. John's Wort, rifampin, cisapride, and in people with known hypersensitivity.
Adult- PO- The recommended dose is 800 mg (four 200-mg capsules) three times daily (every 7-9 hours) with food.
It comes as a capsule to take by mouth, with food.
• Caution should be exercised in patients with history of HIV/AIDS, liver or kidney impairment, Hepatitis B, cirrhosis, organ transplantation, anemia, children, during pregnancy and breastfeeding.
• Most Common :
Fatigue, anemia, nausea/vomiting, headache, and sensory loss.
♦ • Blood : Decrease in white blood cells and anemia.
• Gastrointestinal : Taste disorders, diarrhea and dry mouth.
• General : Fatigue, chills and weakness.
• Metabolic : Decreased appetite.
• Musculoskeletal : Joint pain.
• Central Nervous System : Dizziness, sleeplessness and irritability.
• Respiratory : Difficulty in breathing.
♦ • Skin : Hair loss, dry skin, rash, angioedema, and urticaria.
Avoid excess dosage.
Store it in refrigerator (2-8°C). Do not freeze it.
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