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Last Updated : 10/31/2018

General Information on Baloxavir marboxil

Generic Name : Baloxavir marboxil

Pronunciation : ba-LOX-A-veer mar-BOX-el

Latest prescription information about Baloxavir marboxil. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Antivirals

Trade Names/Brand Names of Baloxavir marboxil

Xofluza

Why is Baloxavir marboxil Prescribed? (Indications)

Baloxavir marboxil tablets are prescribed to treat flu or acute uncomplicated influenza in patients who are aged 12 years and above. It should be taken within 48 hours of the outbreak or onset of the flu symptoms.

Flu is a severe or contagious respiratory illness caused by influenza viruses. Baloxavir marboxil effectively reduces the flu symptoms and the duration of the illness if taken as soon as the symptoms are recognized.

Baloxavir marboxil works by stopping the action of polymerase acidic (PA) protein, a specific protein involved in the multiplication of the virus causing flu or influenza. 

When should Baloxavir marboxil not to be taken? (Contraindications)

Baloxavir marboxil should not be used in patients-

If there is an allergy to baloxavir marboxil
To treat infections other than flu
Children below 12 years of age
Weighing less than 40 kg or 88 pounds
Who received live flu or influenza vaccine very recently

What is the dosage of Baloxavir marboxil?

The dose of baloxavir marboxil is calculated based on the body weight of the individual patient.

The recommended dose of baloxavir marboxil is 40 mg in patients who weigh about 40 kg to 79 kg of body weight.

Patients who weigh 80 kg and above should be prescribed 80 mg of baloxavir marboxil.

How should Baloxavir marboxil be taken?

Baloxavir marboxil is available in a tablet form and should be taken as a single dose orally either with or without food.

Swallow the baloxavir marboxil tablet as a whole with a sufficient quantity of water.

Avoid taking baloxavir marboxil tablets along with milk or milk products, calcium-rich beverages, laxatives for softening the stools, antacids, and oral supplements containing iron, calcium, selenium, zinc, and magnesium.

What are the warnings and precautions for Baloxavir marboxil?

Consult the doctor immediately if the flu symptoms do not get better or if any new symptoms or signs of any illness occur during or after the treatment with baloxavir marboxil.

There is no particular antidote to treat a baloxavir marboxil overdose. Therefore, patients must be provided with adequate supportive therapy and should be treated for the symptoms or signs appropriately under medical supervision.

Caution is required while treating elderly patients and patients with severe liver or kidney damage.

Patients should be advised to inform the doctor before taking a baloxavir marboxil tablet if they are pregnant or breastfeeding.

What are the side effects of Baloxavir marboxil?

The most common side effects of baloxavir marboxil tablets include-

Loose stools
Bronchitis
Nasopharyngitis
Nausea
Headache

What are the other precautions for Baloxavir marboxil?

Do not give or recommend baloxavir marboxil tablets to another person even in the presence of similar symptoms of flu.

What are the Drug Interactions of Baloxavir marboxil?

Before prescribing baloxavir marboxil, the doctor must be informed if the patient is taking or planning to take any prescription drugs, Over-The-Counter (OTC) pills or herbal supplements to avoid dangerous drug interactions.

Patients should be advised to inform the doctor before receiving live flu vaccine after taking the baloxavir marboxil tablets as these may affect the effectiveness of the vaccine.

What are the storage conditions for Baloxavir marboxil?

Store baloxavir marboxil tablets at room temperature between 20C and 25C.

Last Updated : 10/31/2018
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