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General Information on Aztreonam

Generic Name : Aztreonam

Pronunciation : az-TREE-oh-nam

Latest prescription information about Aztreonam. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y40.1 | Therapeutic Classification : Antibiotics

Why is Aztreonam Prescribed? (Indications)

This medication is monobactam antibiotic, prescribed for serious infections caused by susceptible gram negative bacteria like urinary tract infection, lower respiratory tract infection. It works by killing sensitive bacteria that cause infection. 

When should Aztreonam not to be taken? (Contraindications)

Hypersensitivity; lactation

What is the dosage of Aztreonam?

IV/IM -Gram negative infections- 1 to 8 g/day in divided doses depending on severity. Max: 8 g/day.
Urinary tract infection- 0.5 to1 g 8 to12 hours.
IM Cystitis; Gonorrhoea -1 g as a single dose.
Inhalation- 75 mg 3 times daily (at least 4 h apart) for 28 days.

How should Aztreonam be taken?

It is usually administered as an injection at your doctor's office, hospital, or clinic. Inhalation: Do not administer with any other nebulizer.

What are the warnings and precautions for Aztreonam?

Do not use this medication if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials.

Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudo membranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away.

Hypersensitivity to other β-lactams.

Harmful to liver or kidney functions, and pregnancy.

What are the side effects of Aztreonam?

  Central Nervous System: Injection- Seizures, confusion, vertigo, tingling, dizziness.
  Skin: Inhalation- Rash.
Injection- Rash.
  Eye and ENT: Inhalation - Nasal congestion, pharyngolaryngeal pain.
  Gastrointestinal: Inhalation - Abdominal pain, vomiting.
Injection - Diarrhea, nausea, pseudomembranous colitis, vomiting.
  Local: Inflammation of vein after IV administration, pain/swelling at IM injection site.
  Respiratory: Inhalation - Cough, wheezing, asthma.
Injection- Difficulty in breathing.
  Miscellaneous: Inhalation Chest discomfort, fever. Injection - Fever.

What are the other precautions for Aztreonam?

Avoid long-term use, otherwise it will cause secondary infection.

What are the storage conditions for Aztreonam?

Injection: Once reconstituted, it should be used within 48 hr if stored at 15-30C or 7 days if stored at 2-8C. Do not freeze it.

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